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aTYR PHARMA INC

ATYR

$6.17 0.00 (+0.08%) at close

14 Visible periods

31 Metrics

Peer-ranked Benchmarks

Price Chart

Health

Poor

Bearish

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Analytical Summary

aTYR PHARMA INC faces fundamental challenges with weakness in Return on Common Equity (%). The fundamentals warrant careful consideration of downside risks.

Market Cap $573.7M

Dividend Yield —

Revenue Growth -19.1% ↗

Op. Margin None

ROIC -115.0% ↘

FCF / Share $-0.67 ↗

Trailing P/E —

Price / Book 9.0x

FCF Yield —

Debt / Equity —

info Valuation on last close. End-of-day price, Nov 5, 2026.

14-Year Financial Trajectory

Annual

Metric Value Trend Year over Year Percentile

Revenue Total top-line sales

$190.00K

↓ -19.1% —

Net Income Profit after all expenses

$-74.12M

↓ -15.8% —

Operating Margin Operating profit as % of sales

-446.8%

↓ -193.6% —

FCF / Share Free cash flow per share

$-0.67

↑ +28.4% —

Long-Term Debt Long-term obligations

$8.26M

↓ -43.9% —

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Bullish Indicators

No bullish signals detected.

warning

Bearish Risks

Return on Common Equity (%)Return on Common Equity (%) is in the bottom quartile

Health Breakdown

Returns ↓

Financial Health ↓

Cash Quality ↓

Financial view

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📈 Is growth accelerating? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Revenue Growth YoY (%)	-19.1% Weak ↑ Weak Improving Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-339%)	-33.4% Weak Weak Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-518%)	-96.6% Weak Weak Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-1308%)	—	—	2377.5% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+29619%)	—	—	—	—	—	—	—	—
EPS Growth YoY (%)	7.0% Fair ↓ Fair Declining Year-over-year change in earnings per share Optimal: > 10%	8.5% Fair ↓ Fair Declining Year-over-year change in earnings per share Optimal: > 10%	41.3% Excellent Excellent Year-over-year change in earnings per share Optimal: > 10%	9.6% Fair Fair Year-over-year change in earnings per share Optimal: > 10%	—	—	—	—	—	—	—	—	—	—
Net Income Growth YoY (%)	-15.8% Weak ↑ Weak Improving Year-over-year change in net income	-27.1% Weak ↑ Weak Improving Year-over-year change in net income	-11.1% Weak ↑ Weak Improving Year-over-year change in net income	-34.3% Weak ↓ Weak Declining Year-over-year change in net income	-108.1% Weak ↓ Weak Declining Year-over-year change in net income	31.3% Excellent ↑ Excellent Improving Year-over-year change in net income	31.6% Excellent ↑ Excellent Improving Year-over-year change in net income	28.4% Excellent ↑ Excellent Improving Year-over-year change in net income	16.7% Good ↑ Good Improving Year-over-year change in net income	-20.6% Weak ↑ Weak Improving Year-over-year change in net income	-97.0% Weak Weak Year-over-year change in net income	-21.7% Weak Weak Year-over-year change in net income	—	—
FCF Growth YoY (%)	28.4% Excellent ↑ Excellent Improving Year-over-year change in free cash flow	-33.4% Weak ↓ Weak Declining Year-over-year change in free cash flow	54.4% Excellent Excellent Year-over-year change in free cash flow	12.2% Fair Fair Year-over-year change in free cash flow	—	—	—	—	—	—	—	—	—	—
Revenue CAGR 3Y (%)	-73.7% Weak ↓ Weak Declining Compound annual revenue growth over 3 years	—	-67.7% Weak Weak Compound annual revenue growth over 3 years	190.9% Excellent Excellent Compound annual revenue growth over 3 years	—	—	—	—	—	—	—	—	—	—
Revenue CAGR 5Y (%)	-55.1% Weak Weak Compound annual revenue growth over 5 years	-11.0% Weak Weak Compound annual revenue growth over 5 years	—	—	—	—	—	—	—	—	—	—	—	—

💰 Are margins durable? 5 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Operating Margin (%) (%)	—	—	—	-446.8% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-3079%)	—	-152.2% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1115%)	—	—	—	—	—	—	—	—
Effective Tax Rate (%) (%)	0.0% Excellent → Excellent Stable Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.0% Excellent → Excellent Stable Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.0% Excellent → Excellent Stable Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.0% Excellent → Excellent Stable Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.0% Excellent → Excellent Stable Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.0% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.0% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	—	—	0.1% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	—	—	—	—
Profit Margin (%) (%)	—	—	—	-436.5% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-3738%)	—	-155.2% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1393%)	—	—	—	—	—	—	—	—
FCF Margin (%) (%)	—	—	—	-419.1% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	—	-148.3% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	—	—	—	—	—	—	—	—
FCF / Net Income (x)	0.84x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	1.08x Fair ↑ Fair Improving Free cash flow relative to reported net income Optimal: > 1x	0.74x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.96x Caution → Caution Stable Free cash flow relative to reported net income Optimal: > 1x	0.99x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.96x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.85x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.92x Caution Caution Free cash flow relative to reported net income Optimal: > 1x	0.91x Caution Caution Free cash flow relative to reported net income Optimal: > 1x	—	—	—	—	—

🎯 Is capital allocation efficient? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Return on Invested Capital (%)	-115.0% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-97.0% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-60.6% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-64.9% Weak → Weak Stable Return earned on debt + equity capital invested Optimal: > 10%	-31.1% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-50.3% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-108.5% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-61.9% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-47.2% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-80.4% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-32.2% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	20.4% Excellent Excellent Return earned on debt + equity capital invested Optimal: > 10%	23.4% Excellent Excellent Return earned on debt + equity capital invested Optimal: > 10%	—
Return on Capital (%) (%)	-83.5% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-70.1% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-45.5% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-48.4% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-29.4% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-41.1% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-63.5% Weak → Weak Stable Operating profit relative to total assets Optimal: > 10%	-62.2% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-52.8% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-72.0% Weak → Weak Stable Operating profit relative to total assets Optimal: > 10%	-36.7% Weak Weak Operating profit relative to total assets Optimal: > 10%	-114.1% Weak Weak Operating profit relative to total assets Optimal: > 10%	—	—
Return on Common Equity (%) (%)	-109.8% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-832%)	-91.4% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-710%)	-55.6% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-471%)	-63.4% Weak → Weak Stable Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-523%)	-30.9% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-306%)	-51.3% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-442%)	-111.4% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-843%)	-102.6% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-784%)	-75.0% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-600%)	-92.1% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-714%)	-41.7% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-378%)	26.8% Excellent Excellent Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+78%)	30.3% Excellent Excellent Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+102%)	—

⚖️ Is the balance sheet risky? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Debt to Equity (x)	—	—	—	—	—	—	—	0.25x Excellent ↑ Excellent Improving Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-59%)	0.23x Excellent ↑ Excellent Improving Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-62%)	0.15x Excellent Excellent Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-76%)	0.02x Excellent Excellent Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-97%)	—	—	—
Interest Coverage (x)	-825.82x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-495.72x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-319.30x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-859.33x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	—	-51.66x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-20.48x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-19.31x Weak Weak Operating income divided by interest expense Optimal: > 5x	-47.15x Weak Weak Operating income divided by interest expense Optimal: > 5x	—	—	—	—	—
Net Debt (USD)	$-10.74M	$-11.05M	$-22.54M	$-9.98M	$-2.34M	$-16.95M	$-9.21M	$-14.70M	$-6.37M	$-29.19M	$-51.25M	$-13.90M	$-36.46M	$-3.67M
Debt / EBITDA (x)	—	—	—	—	—	—	—	-0.26x Excellent ↓ Excellent Declining Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	-0.32x Excellent ↓ Excellent Declining Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	-0.16x Excellent Excellent Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	-0.04x Excellent Excellent Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	—	—	—

📊 What does each share earn? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Revenue per Share (USD)	$0.00	$0.00	$0.01	$0.37	—	—	—	—	—	—	—	—	—	—
Basic EPS, GAAP (USD)	$-0.80	$-0.86	$-0.94	$-1.60	$-1.77	—	—	—	—	—	—	—	—	—
Free Cash Flow per Share (USD)	$-0.67	$-0.93	$-0.70	$-1.53	$-1.74	—	—	—	—	—	—	—	—	—
Book Value per Share (USD)	$0.69	$0.83	$1.43	$2.42	$3.93	$2.87	$5.44	$15.39	$2.16	$2.64	$4.86	$-100.02	—	—
Tangible Book Value per Share (USD)	$0.69	$0.83	$1.43	$2.42	$3.93	$2.87	$5.44	$15.39	$2.16	$2.64	$4.86	$-100.02	—	—
Basic Weighted Avg Shares (shares)	92.99M	74.26M	53.61M	28.42M	19.08M	—	—	—	—	—	—	—	—	—

🏦 How resilient is the balance sheet? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Working Capital (USD)	$65.09M	$66.99M	$86.58M	$67.01M	$107.56M	$29.67M	$19.00M	$39.97M	$76.59M	$66.24M	$85.80M	$6.40M	—	—
LT Debt (USD)	—	—	—	—	—	—	—	$8.26M	$14.72M	$9.20M	$1.78M	—	—	—
Total Equity (USD)	$67.48M	$70.02M	$90.66M	$71.46M	$109.30M	$31.65M	$21.19M	$33.65M	$64.25M	$62.80M	$115.05M	$-91.01M	$-66.08M	$-64.55M

📋 What is driving earnings? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Sales/Revenue/Turnover (USD)	$190.00K	$235.00K	$353.00K	$10.39M	—	$10.46M	$422.00K	—	—	—	—	—	—	—
Depreciation Expense (USD)	$664.00K	$708.00K	$592.00K	$232.00K	$475.00K	$569.00K	$635.00K	$746.00K	$713.00K	$900.00K	$869.00K	$829.00K	$714.00K	—
Net Income, GAAP (USD)	$-74.12M	$-64.02M	$-50.39M	$-45.34M	$-33.77M	$-16.22M	$-23.60M	$-34.52M	$-48.21M	$-57.85M	$-47.97M	$-24.35M	$-20.01M	—
Operating Cash Flow (USD)	$-61.99M	$-69.12M	$-33.22M	$-41.89M	$-33.08M	$-15.30M	$-20.01M	$-31.06M	$-42.36M	—	—	—	—	—

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bar_chart Data from SEC EDGAR XBRL filings

Synced 4 days ago 14 years · 52 quarters

aTYR PHARMA INC

Analytical Summary

14-Year Financial Trajectory

Bullish Indicators

Bearish Risks

Health Breakdown

Statement lens

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