Autolus Therapeutics plc
AUTLAnalytical Summary
Autolus Therapeutics plc faces fundamental challenges with weakness in Return on Common Equity (%). The fundamentals warrant careful consideration of downside risks.
11-Year Financial Trajectory
AnnualBullish Indicators
- No bullish signals detected.
Bearish Risks
- Operating Margin (%)Operating Margin (%) is in the bottom quartile
- Profit Margin (%)Profit Margin (%) is in the bottom quartile
- Return on Common Equity (%)Return on Common Equity (%) is in the bottom quartile
Health Breakdown
Statement lens
Choose the reporting cadence, isolate a period range, or search directly for a metric.
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Mar 31, 2022 10-K ↗ | FY 2020 Dec 31, 2020 20-F ↗ | FY 2019 Dec 31, 2019 20-F ↗ | FY 2018 Dec 31, 2018 20-F ↗ | FY 2017 Sep 30, 2017 20-F ↗ | FY 2016 Sep 30, 2016 20-F ↗ | FY 2015 Sep 30, 2015 20-F ↗ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue Growth YoY (%) |
644.9%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+7962%)
|
496.0%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+6100%)
|
— | — | — | — |
106.7%
Excellent
↑
Excellent
Improving
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+1234%)
|
-16.9%
Weak
Weak
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Below avg (-311%)
|
39.7%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+396%)
|
— | — |
| EPS Growth YoY (%) |
-25.6%
Weak
↓
Weak
Declining
Year-over-year change in earnings per share
Optimal:
> 10%
|
28.3%
Excellent
↑
Excellent
Improving
Year-over-year change in earnings per share
Optimal:
> 10%
|
23.6%
Good
→
Good
Stable
Year-over-year change in earnings per share
Optimal:
> 10%
|
20.3%
Good
Good
Year-over-year change in earnings per share
Optimal:
> 10%
|
28.6%
Excellent
Excellent
Year-over-year change in earnings per share
Optimal:
> 10%
|
— | — | — | — | — | — |
| Net Income Growth YoY (%) |
-30.3%
Weak
↓
Weak
Declining
Year-over-year change in net income |
-5.9%
Weak
↑
Weak
Improving
Year-over-year change in net income |
-40.0%
Weak
↓
Weak
Declining
Year-over-year change in net income |
-4.7%
Weak
↑
Weak
Improving
Year-over-year change in net income |
-0.0%
Weak
↑
Weak
Improving
Year-over-year change in net income |
-14.7%
Weak
↑
Weak
Improving
Year-over-year change in net income |
-176.8%
Weak
↓
Weak
Declining
Year-over-year change in net income |
-126.9%
Weak
Weak
Year-over-year change in net income |
-57.2%
Weak
Weak
Year-over-year change in net income |
— | — |
| FCF Growth YoY (%) |
-27.1%
Weak
↓
Weak
Declining
Year-over-year change in free cash flow |
0.6%
Caution
↓
Caution
Declining
Year-over-year change in free cash flow |
30.6%
Excellent
↑
Excellent
Improving
Year-over-year change in free cash flow |
26.3%
Excellent
Excellent
Year-over-year change in free cash flow |
31.6%
Excellent
Excellent
Year-over-year change in free cash flow |
— | — | — | — | — | — |
| Revenue CAGR 3Y (%) | — | — | — | — | — | — |
33.9%
Excellent
Excellent
Compound annual revenue growth over 3 years |
— | — | — | — |
| Revenue CAGR 5Y (%) | — |
28.3%
Excellent
Excellent
Compound annual revenue growth over 5 years |
3.8%
Caution
Caution
Compound annual revenue growth over 5 years |
— | — | — | — | — | — | — | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Mar 31, 2022 10-K ↗ | FY 2020 Dec 31, 2020 20-F ↗ | FY 2019 Dec 31, 2019 20-F ↗ | FY 2018 Dec 31, 2018 20-F ↗ | FY 2017 Sep 30, 2017 20-F ↗ | FY 2016 Sep 30, 2016 20-F ↗ | FY 2015 Sep 30, 2015 20-F ↗ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin (%) (%) |
-358.9%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-2492%)
|
— | — | — | — | — | — | — | — | — | — |
| Effective Tax Rate (%) (%) |
-0.7%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-0.7%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
0.0%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-0.2%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-0.0%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
14.5%
Excellent
↑
Excellent
Improving
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
10.9%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
14.0%
Excellent
→
Excellent
Stable
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
15.6%
Good
Good
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
12.4%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
— |
| Profit Margin (%) (%) |
-381.4%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-3278%)
|
— | — | — | — | — | — | — | — | — | — |
| FCF Margin (%) (%) |
-401.4%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
— | — | — | — | — | — | — | — | — | — |
| FCF / Net Income (x) |
1.05x
Fair
↑
Fair
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.03x
Fair
↑
Fair
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.75x
Caution
↓
Caution
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.83x
Caution
↓
Caution
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.89x
Caution
→
Caution
Stable
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.93x
Caution
→
Caution
Stable
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.97x
Caution
→
Caution
Stable
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.91x
Caution
→
Caution
Stable
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.98x
Caution
Caution
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.93x
Caution
Caution
Free cash flow relative to reported net income
Optimal:
> 1x
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Mar 31, 2022 10-K ↗ | FY 2020 Dec 31, 2020 20-F ↗ | FY 2019 Dec 31, 2019 20-F ↗ | FY 2018 Dec 31, 2018 20-F ↗ | FY 2017 Sep 30, 2017 20-F ↗ | FY 2016 Sep 30, 2016 20-F ↗ | FY 2015 Sep 30, 2015 20-F ↗ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Return on Invested Capital (%) |
-152.9%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-56.9%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-161.2%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-89.2%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-45.0%
Weak
→
Weak
Stable
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-68.4%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-51.1%
Weak
Weak
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-19.3%
Weak
Weak
Return earned on debt + equity capital invested
Optimal:
> 10%
|
— | — | — |
| Return on Capital (%) (%) |
-45.9%
Weak
→
Weak
Stable
Operating profit relative to total assets
Optimal:
> 10%
|
-30.8%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-47.9%
Weak
→
Weak
Stable
Operating profit relative to total assets
Optimal:
> 10%
|
-54.4%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-38.8%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-57.1%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-48.1%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
-22.6%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
— | — | — |
| Return on Common Equity (%) (%) |
-161.4%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-1176%)
|
-51.6%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-444%)
|
-186.9%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-1346%)
|
-92.4%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-716%)
|
-45.4%
Weak
→
Weak
Stable
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-402%)
|
-67.7%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-551%)
|
-48.6%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-424%)
|
-17.5%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-217%)
|
-13.8%
Weak
Weak
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-192%)
|
-40.9%
Weak
Weak
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-373%)
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Mar 31, 2022 10-K ↗ | FY 2020 Dec 31, 2020 20-F ↗ | FY 2019 Dec 31, 2019 20-F ↗ | FY 2018 Dec 31, 2018 20-F ↗ | FY 2017 Sep 30, 2017 20-F ↗ | FY 2016 Sep 30, 2016 20-F ↗ | FY 2015 Sep 30, 2015 20-F ↗ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt to Equity (x) | — | — | — | — | — | — |
0.00x
Excellent
↓
Excellent
Declining
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-100%)
|
0.00x
Excellent
Excellent
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-100%)
|
0.01x
Excellent
Excellent
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-99%)
|
— | — |
| Interest Coverage (x) |
-7.38x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-25.98x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-3.99x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-16.10x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-127.65x
Weak
Weak
Operating income divided by interest expense
Optimal:
> 5x
|
— |
-95.16x
Weak
Weak
Operating income divided by interest expense
Optimal:
> 5x
|
— | — | — | — |
| Net Debt (USD) | $-104.13M | $-227.38M | $-239.57M | $-163.05M | $-310.34M | — | $0.00 | $285.00K | $763.00K | — | — |
| Debt / EBITDA (x) | — | — | — | — | — | — |
0.00x
Excellent
Excellent
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-0.01x
Excellent
Excellent
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
— | — | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Mar 31, 2022 10-K ↗ | FY 2020 Dec 31, 2020 20-F ↗ | FY 2019 Dec 31, 2019 20-F ↗ | FY 2018 Dec 31, 2018 20-F ↗ | FY 2017 Sep 30, 2017 20-F ↗ | FY 2016 Sep 30, 2016 20-F ↗ | FY 2015 Sep 30, 2015 20-F ↗ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Working Capital (USD) | $362.48M | $600.19M | $230.56M | $173.49M | $280.62M | $163.35M | $224.27M | $211.89M | $137.45M | — | — |
| LT Debt (USD) | — | — | — | — | — | — | $0.00 | $285.00K | $763.00K | — | — |
| Total Equity (USD) | $178.13M | $427.32M | $111.47M | $161.15M | $313.32M | $210.03M | $254.84M | $255.47M | $142.60M | $30.69M | $10.50M |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Mar 31, 2022 10-K ↗ | FY 2020 Dec 31, 2020 20-F ↗ | FY 2019 Dec 31, 2019 20-F ↗ | FY 2018 Dec 31, 2018 20-F ↗ | FY 2017 Sep 30, 2017 20-F ↗ | FY 2016 Sep 30, 2016 20-F ↗ | FY 2015 Sep 30, 2015 20-F ↗ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue/Turnover (USD) | $75.39M | $10.12M | $1.70M | — | — | — | $2.91M | $1.41M | $1.69M | $1.21M | — |
| Depreciation Expense (USD) | $8.30M | $7.55M | $6.57M | $7.42M | $8.46M | $5.66M | $4.61M | $1.71M | $1.01M | $478.00K | — |
| Net Income, GAAP (USD) | $-287.53M | $-220.66M | $-208.38M | $-148.84M | $-142.10M | $-142.09M | $-123.85M | $-44.75M | $-19.73M | $-12.55M | — |
| Operating Cash Flow (USD) | $-283.57M | $-206.27M | $-145.59M | $-112.31M | $-117.86M | $-117.76M | $-101.48M | $-31.54M | $-16.36M | $-9.85M | — |
Secondary lens
Benchmark Lens
Compare AUTL against peers after checking the statement evidence.
Open lens
Benchmark Lens
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Signals
Key bullish and bearish indicators for AUTL
No bullish signals detected
Operating Margin (%) is in the bottom quartile
Profit Margin (%) is in the bottom quartile
Return on Common Equity (%) is in the bottom quartile
Percentile Rankings
How AUTL compares to all companies
Peer Comparison
AUTL vs similar peers
Compare AUTL with peers
Stack AUTL against similar companies across every metric on this page.
north_east Open comparisonbar_chart Data from SEC EDGAR XBRL filings
Synced 1 week ago 11 years · 30 quarters