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Cocrystal Pharma, Inc.

COCP

$1.00 ▼ -0.09 (-8.26%) at close

17 Visible periods

27 Metrics

Peer-ranked Benchmarks

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Health

Poor

Bearish

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Analytical Summary

Cocrystal Pharma, Inc. faces fundamental challenges with weakness in Return on Common Equity (%). The fundamentals warrant careful consideration of downside risks.

Market Cap $11.3M

Dividend Yield —

Revenue Growth None

Op. Margin None

ROIC -112.5% ↗

FCF / Share $-0.73 ↗

Trailing P/E —

Price / Book 2.2x

FCF Yield —

Debt / Equity —

info Valuation on last close. End-of-day price, Nov 5, 2026.

17-Year Financial Trajectory

Annual

Metric Value Trend Year over Year Percentile

Revenue Total top-line sales

$2.01M

↓ -69.3% —

Net Income Profit after all expenses

$-8.83M

↑ +49.5% —

Operating Margin Operating profit as % of sales

-476.0%

↓ -1456.6% —

FCF / Share Free cash flow per share

$-0.73

↑ +55.2% —

Long-Term Debt Long-term obligations

$49.94M

↓ -23.5% —

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Bullish Indicators

No bullish signals detected.

warning

Bearish Risks

Return on Common Equity (%)Return on Common Equity (%) is in the bottom quartile

Health Breakdown

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Financial view

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📈 Is growth accelerating? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗
Revenue Growth YoY (%)	—	—	—	—	—	-69.3% Weak Weak Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-966%)	—	—	—	—	—	—	—	—	—	—	—
EPS Growth YoY (%)	54.7% Excellent ↑ Excellent Improving Year-over-year change in earnings per share Optimal: > 10%	8.0% Fair ↑ Fair Improving Year-over-year change in earnings per share Optimal: > 10%	60.8% Excellent Excellent Year-over-year change in earnings per share Optimal: > 10%	-2881.2% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	—	—	—	—	—	-3875.0% Weak ↓ Weak Declining Year-over-year change in earnings per share Optimal: > 10%	—	100.0% Excellent ↑ Excellent Improving Year-over-year change in earnings per share Optimal: > 10%	46.2% Excellent ↑ Excellent Improving Year-over-year change in earnings per share Optimal: > 10%	-18.2% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	-1000.0% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	—	—
Net Income Growth YoY (%)	49.5% Excellent ↑ Excellent Improving Year-over-year change in net income	2.7% Caution ↑ Caution Improving Year-over-year change in net income	53.7% Excellent ↑ Excellent Improving Year-over-year change in net income	-173.8% Weak ↓ Weak Declining Year-over-year change in net income	-47.0% Weak ↑ Weak Improving Year-over-year change in net income	80.0% Excellent ↑ Excellent Improving Year-over-year change in net income	1.8% Caution ↑ Caution Improving Year-over-year change in net income	-7901.3% Weak ↑ Weak Improving Year-over-year change in net income	99.2% Excellent ↑ Excellent Improving Year-over-year change in net income	-49.4% Weak ↑ Weak Improving Year-over-year change in net income	-50528.3% Weak ↓ Weak Declining Year-over-year change in net income	97.5% Excellent ↑ Excellent Improving Year-over-year change in net income	51.2% Excellent ↑ Excellent Improving Year-over-year change in net income	-45.9% Weak Weak Year-over-year change in net income	-1606.4% Weak Weak Year-over-year change in net income	—	—
FCF Growth YoY (%)	55.2% Excellent ↑ Excellent Improving Year-over-year change in free cash flow	-5.8% Weak ↓ Weak Declining Year-over-year change in free cash flow	42.0% Excellent Excellent Year-over-year change in free cash flow	-52.3% Weak Weak Year-over-year change in free cash flow	—	—	—	-3.2% Weak ↓ Weak Declining Year-over-year change in free cash flow	54.0% Excellent → Excellent Stable Year-over-year change in free cash flow	96.3% Excellent Excellent Year-over-year change in free cash flow	8.1% Fair Fair Year-over-year change in free cash flow	—	—	—	—	—	—

💰 Are margins durable? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗
Operating Margin (%) (%)	—	—	—	—	—	-476.0% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-3273%)	—	—	—	—	—	—	—	—	-30.6% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-304%)	—	—
Profit Margin (%) (%)	—	—	—	—	—	-479.0% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-4092%)	—	—	—	—	—	—	—	—	-42.9% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-458%)	—	—
FCF Margin (%) (%)	—	—	—	—	—	-500.0% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	-26.0% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	—	—	—	—	—	—	—	—	—	—
FCF / Net Income (x)	0.93x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.94x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.82x Caution → Caution Stable Free cash flow relative to reported net income Optimal: > 1x	0.55x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	0.90x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	1.04x Fair ↓ Fair Declining Free cash flow relative to reported net income Optimal: > 1x	0.04x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	0.17x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	11.33x Excellent ↓ Excellent Declining Free cash flow relative to reported net income Optimal: > 1x	0.20x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	0.21x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	60.75x Excellent ↑ Excellent Improving Free cash flow relative to reported net income Optimal: > 1x	0.95x Caution Caution Free cash flow relative to reported net income Optimal: > 1x	0.22x Weak Weak Free cash flow relative to reported net income Optimal: > 1x	—	—	—

🎯 Is capital allocation efficient? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗
Return on Invested Capital (%)	-112.5% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-148.3% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-55.6% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-77.5% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-14.5% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-14.4% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-148.8% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-74.3% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-6.2% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-81.7% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-19.6% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-6.4% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	36.5% Excellent ↓ Excellent Declining Return earned on debt + equity capital invested Optimal: > 10%	56.3% Excellent → Excellent Stable Return earned on debt + equity capital invested Optimal: > 10%	110.9% Excellent Excellent Return earned on debt + equity capital invested Optimal: > 10%	4.3% Caution Caution Return earned on debt + equity capital invested Optimal: > 10%	—
Return on Capital (%) (%)	-92.9% Weak → Weak Stable Operating profit relative to total assets Optimal: > 10%	-132.9% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-59.4% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-95.1% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-17.9% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-17.7% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-169.7% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-91.8% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-6.8% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-84.7% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-24.1% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-2.2% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-245.7% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-35.3% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-51.5% Weak Weak Operating profit relative to total assets Optimal: > 10%	-0.4% Weak Weak Operating profit relative to total assets Optimal: > 10%	—
Return on Common Equity (%) (%)	-139.5% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1030%)	-183.8% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1325%)	-68.2% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-554%)	-98.2% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-754%)	-18.3% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-222%)	-18.4% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-223%)	-187.4% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1349%)	-73.3% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-589%)	-0.6% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-104%)	-73.2% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-588%)	-29.9% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-299%)	-1.5% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-110%)	44.0% Excellent ↓ Excellent Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+193%)	222.5% Excellent ↑ Excellent Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+1383%)	197.1% Excellent Excellent Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+1214%)	54.3% Excellent Excellent Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+262%)	—

⚖️ Is the balance sheet risky? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗
Debt to Equity (x)	—	—	—	—	—	—	—	—	—	—	0.30x Excellent Excellent Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-50%)	9.81x Weak Weak Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Above avg (+1535%)	—	—	—	—	—
Interest Coverage (x)	—	—	-29.00x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-19414.50x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-3555.25x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-1198.25x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-2547.68x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-1084.90x Weak Weak Operating income divided by interest expense Optimal: > 5x	-1180.29x Weak Weak Operating income divided by interest expense Optimal: > 5x	—	—	—	—	-0.49x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-3.13x Weak Weak Operating income divided by interest expense Optimal: > 5x	-0.07x Weak Weak Operating income divided by interest expense Optimal: > 5x	—
Net Debt (USD)	$-7.03M	$-9.86M	$-26.35M	$-37.14M	—	$-33.01M	—	—	—	$-3.60M	$40.66M	$61.29M	$-1.03M	$-8.10K	$-416.33K	$-251.47K	$-587.41K
Debt / EBITDA (x)	—	—	—	—	—	—	—	—	—	—	-0.93x Excellent Excellent Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	-11.65x Excellent Excellent Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	—	—	—	—	—

📊 What does each share earn? 5 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗
Basic EPS, GAAP (USD)	$-0.78	$-1.72	$-1.87	$-4.77	$-0.16	—	—	—	—	$-3.18	$-0.08	$0.00	$-0.07	$-0.13	$-0.11	$-0.01	—
Free Cash Flow per Share (USD)	$-0.73	$-1.62	$-1.53	$-2.64	$-1.73	—	—	$-0.30	$-0.29	$-0.63	$-16.91	$-18.40	—	—	—	—	—
Book Value per Share (USD)	$0.46	$0.94	$2.59	$4.86	$9.52	$0.75	$0.73	$2.23	$4.34	$4.30	$241.35	$54.30	—	$-0.06	$-0.05	$-0.01	—
Tangible Book Value per Share (USD)	$0.46	$0.94	$2.59	$4.86	$7.18	$0.47	$0.19	$0.06	$1.66	$1.56	$147.46	$-477.93	—	$-0.06	$-0.07	$-0.01	—
Basic Weighted Avg Shares (shares)	11.29M	10.17M	9.65M	8.14M	7.36M	—	31,859	28.01M	24.13M	23.52M	630,316	326,779	57,255	—	—	—	—

🏦 How resilient is the balance sheet? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗
Working Capital (USD)	$5.92M	$9.15M	$25.83M	$38.96M	$57.78M	$32.66M	$6.00M	$1.39M	$739.00K	$3.43M	$3.22M	$-2.78M	$787.00K	$-4.13M	$-4.37M	$-885.30K	—
LT Debt (USD)	—	—	—	—	—	—	—	—	—	—	$49.94M	$65.26M	—	—	—	—	—
Total Equity (USD)	$6.33M	$9.52M	$26.38M	$39.57M	$77.55M	$52.51M	$25.71M	$66.89M	$105.40M	$102.32M	$167.59M	$6.65M	$-8.83M	$-3.58M	$-2.77M	$-589.20K	$-226.36K

📋 What is driving earnings? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗
Sales/Revenue/Turnover (USD)	—	—	—	—	—	$2.01M	$6.56M	—	—	—	—	—	—	—	$12.71M	—	—
Depreciation Expense (USD)	—	—	—	—	—	—	—	$50.00K	$101.00K	$201.00K	$192.00K	$199.00K	$236.00K	—	—	—	—
Net Income, GAAP (USD)	$-8.83M	$-17.50M	$-17.98M	$-38.84M	$-14.19M	$-9.65M	$-48.17M	$-49.05M	$-613.00K	$-74.87M	$-50.12M	$-99.00K	$-3.89M	$-7.96M	$-5.46M	$-319.81K	—
Operating Cash Flow (USD)	$-8.19M	$-16.48M	$-14.67M	$-21.43M	$-12.72M	$-9.83M	$-1.56M	$-8.29M	$-6.90M	$-14.65M	$-10.32M	$-6.01M	$-3.69M	$-1.59M	—	—	—

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bar_chart Data from SEC EDGAR XBRL filings

Synced 5 days ago 17 years · 65 quarters

Cocrystal Pharma, Inc.

Analytical Summary

17-Year Financial Trajectory

Bullish Indicators

Bearish Risks

Health Breakdown

Statement lens

Benchmark Lens

Signals

Percentile Rankings

Peer Comparison

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