Monte Rosa Therapeutics, Inc.
GLUEAnalytical Summary
Monte Rosa Therapeutics, Inc. faces fundamental challenges with weakness in Profit Margin (%) and Operating Margin (%). The fundamentals warrant careful consideration of downside risks.
6-Year Financial Trajectory
AnnualBullish Indicators
- No bullish signals detected.
Bearish Risks
- Operating Margin (%)Operating Margin (%) is in the bottom quartile
- Profit Margin (%)Profit Margin (%) is in the bottom quartile
Health Breakdown
Statement lens
Choose the reporting cadence, isolate a period range, or search directly for a metric.
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ |
|---|---|---|---|---|---|---|
| Revenue Growth YoY (%) |
63.5%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+694%)
|
— | — | — | — | — |
| Net Income Growth YoY (%) |
46.9%
Excellent
↑
Excellent
Improving
Year-over-year change in net income |
46.3%
Excellent
↑
Excellent
Improving
Year-over-year change in net income |
-24.7%
Weak
↑
Weak
Improving
Year-over-year change in net income |
-46.7%
Weak
Weak
Year-over-year change in net income |
-106.1%
Weak
Weak
Year-over-year change in net income |
— |
| FCF Growth YoY (%) | N/M | N/M |
45.2%
Excellent
Excellent
Year-over-year change in free cash flow |
19.3%
Good
Good
Year-over-year change in free cash flow |
— | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ |
|---|---|---|---|---|---|---|
| Operating Margin (%) (%) |
-43.8%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-392%)
|
-107.3%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-815%)
|
— | — | — | — |
| Effective Tax Rate (%) (%) |
2.8%
Excellent
↑
Excellent
Improving
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-3.7%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-0.3%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
0.0%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
— | — |
| Profit Margin (%) (%) |
-31.2%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-360%)
|
-96.1%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-901%)
|
— | — | — | — |
| FCF Margin (%) (%) |
-22.2%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
50.3%
Excellent
Excellent
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
— | — | — | — |
| FCF / Net Income (x) |
0.71x
Caution
↑
Caution
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
-0.52x
Weak
↓
Weak
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.46x
Weak
↓
Weak
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.97x
Caution
↑
Caution
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.93x
Caution
Caution
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.74x
Caution
Caution
Free cash flow relative to reported net income
Optimal:
> 1x
|
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ |
|---|---|---|---|---|---|---|
| Return on Invested Capital (%) |
-22.6%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-37.7%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-80.2%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-41.4%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-16.6%
Weak
Weak
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-45.4%
Weak
Weak
Return earned on debt + equity capital invested
Optimal:
> 10%
|
| Return on Capital (%) (%) |
-12.1%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-18.5%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-47.2%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-32.8%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-19.9%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
-56.7%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
| Return on Common Equity (%) (%) |
-16.6%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-210%)
|
-32.6%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-317%)
|
-75.5%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-603%)
|
-40.0%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-367%)
|
-21.3%
Weak
Weak
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-242%)
|
-73.6%
Weak
Weak
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-591%)
|
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ |
|---|---|---|---|---|---|---|
| Working Capital (USD) | $328.97M | $220.49M | $189.62M | $250.32M | $332.03M | $14.32M |
| Total Equity (USD) | $233.06M | $222.94M | $179.25M | $271.41M | $347.51M | $48.73M |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ |
|---|---|---|---|---|---|---|
| Sales/Revenue/Turnover (USD) | $123.67M | $75.62M | $0.00 | — | — | — |
| Depreciation Expense (USD) | $8.36M | $8.12M | $6.22M | $3.75M | $2.13M | $537.00K |
| Net Income, GAAP (USD) | $-38.63M | $-72.70M | $-135.35M | $-108.50M | $-73.96M | $-35.88M |
| Operating Cash Flow (USD) | $-22.80M | $42.00M | $-43.80M | $-92.47M | $-59.36M | $-23.05M |
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Signals
Key bullish and bearish indicators for GLUE
No bullish signals detected
Operating Margin (%) is in the bottom quartile
Profit Margin (%) is in the bottom quartile
Percentile Rankings
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Peer Comparison
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Synced 1 week ago 6 years · 26 quarters