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IOVANCE BIOTHERAPEUTICS, INC.

IOVA

$6.33 ▲ +0.16 (+2.51%) at close

19 Visible periods

25 Metrics

Peer-ranked Benchmarks

Price Chart

Health

Poor

Bearish

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Analytical Summary

IOVANCE BIOTHERAPEUTICS, INC. faces fundamental challenges with weakness in Return on Common Equity (%) and Profit Margin (%). The fundamentals warrant careful consideration of downside risks.

Market Cap $2.3M

Dividend Yield —

Revenue Growth 60.6% ↘

Op. Margin -153.1% ↗

ROIC -57.4% ↘

FCF / Share $-940.95

Trailing P/E —

Price / Book 3.7x

FCF Yield —

Debt / Equity —

info Valuation on last close. End-of-day price, Aug 7, 2026.

19-Year Financial Trajectory

Annual

Metric Value Trend Year over Year Percentile

Revenue Total top-line sales

$263.50M

↑ +60.6% —

Net Income Profit after all expenses

$-390.98M

↓ -5.1% —

Operating Margin Operating profit as % of sales

-153.1%

↑ +36.5% 1th

trending_up

Bullish Indicators

No bullish signals detected.

warning

Bearish Risks

Operating Margin (%)Operating Margin (%) is in the bottom quartile
Profit Margin (%)Profit Margin (%) is in the bottom quartile
Return on Common Equity (%)Return on Common Equity (%) is in the bottom quartile

Health Breakdown

Profitability ↑

Returns →

Cash Quality ↑

Financial view

Statement lens

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Cadence

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📈 Is growth accelerating? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 16, 2007 10-K ↗
Revenue Growth YoY (%)	60.6% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+658%)	13699.0% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+171137%)	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—
EPS Growth YoY (%)	14.8% Fair → Fair Stable Year-over-year change in earnings per share Optimal: > 10%	32.3% Excellent ↑ Excellent Improving Year-over-year change in earnings per share Optimal: > 10%	24.1% Good ↑ Good Improving Year-over-year change in earnings per share Optimal: > 10%	-11.7% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	-18.6% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	—	—	—	—	—	—	—	—	—	—	—	—	—	—
Net Income Growth YoY (%)	-5.1% Weak ↓ Weak Declining Year-over-year change in net income	16.2% Good ↑ Good Improving Year-over-year change in net income	-12.2% Weak ↑ Weak Improving Year-over-year change in net income	-15.7% Weak ↑ Weak Improving Year-over-year change in net income	-31.8% Weak ↑ Weak Improving Year-over-year change in net income	-31.4% Weak ↑ Weak Improving Year-over-year change in net income	-59.9% Weak ↑ Weak Improving Year-over-year change in net income	-34.2% Weak ↑ Weak Improving Year-over-year change in net income	-74.1% Weak ↓ Weak Declining Year-over-year change in net income	-91.2% Weak ↑ Weak Improving Year-over-year change in net income	-129.8% Weak ↑ Weak Improving Year-over-year change in net income	52.6% Excellent ↑ Excellent Improving Year-over-year change in net income	-667.4% Weak ↑ Weak Improving Year-over-year change in net income	87.9% Excellent ↑ Excellent Improving Year-over-year change in net income	-1602.5% Weak ↑ Weak Improving Year-over-year change in net income	-10095.2% Weak Weak Year-over-year change in net income	73.1% Excellent Excellent Year-over-year change in net income	—	—

💰 Are margins durable? 5 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 16, 2007 10-K ↗
Operating Margin (%) (%)	-153.1% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1121%)	-240.9% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1706%)	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—
Effective Tax Rate (%) (%)	0.5% Excellent → Excellent Stable Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.8% Excellent ↑ Excellent Improving Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.8% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.0% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—
Profit Margin (%) (%)	-148.4% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1336%)	-226.8% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1990%)	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—
FCF Margin (%) (%)	-127.6% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	-221.9% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—
FCF / Net Income (x)	0.86x Caution → Caution Stable Free cash flow relative to reported net income Optimal: > 1x	0.98x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.87x Caution → Caution Stable Free cash flow relative to reported net income Optimal: > 1x	0.79x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.78x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.97x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.84x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.83x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.87x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.65x Weak Weak Free cash flow relative to reported net income Optimal: > 1x	—	-0.59x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	—	0.68x Weak ↑ Weak Improving Free cash flow relative to reported net income Optimal: > 1x	0.25x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	0.39x Weak Weak Free cash flow relative to reported net income Optimal: > 1x	0.92x Caution Caution Free cash flow relative to reported net income Optimal: > 1x	—	—

🎯 Is capital allocation efficient? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 16, 2007 10-K ↗
Return on Invested Capital (%)	-57.4% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-55.2% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-78.2% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-79.8% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-43.6% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-31.5% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-54.7% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-21.7% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-50.4% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-25.4% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-21.2% Weak → Weak Stable Return earned on debt + equity capital invested Optimal: > 10%	-21.2% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-101.6% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	56.8% Excellent ↑ Excellent Improving Return earned on debt + equity capital invested Optimal: > 10%	136.7% Excellent ↑ Excellent Improving Return earned on debt + equity capital invested Optimal: > 10%	-101.0% Weak Weak Return earned on debt + equity capital invested Optimal: > 10%	92.4% Excellent Excellent Return earned on debt + equity capital invested Optimal: > 10%	—	—
Return on Capital (%) (%)	-44.2% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-43.4% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-59.0% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-60.1% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-44.1% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-34.1% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-60.0% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-26.7% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-59.8% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-31.2% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-26.4% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-25.9% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-113.9% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-27649.5% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-3889.3% Weak Weak Operating profit relative to total assets Optimal: > 10%	-55.8% Weak Weak Operating profit relative to total assets Optimal: > 10%	—	—	—
Return on Common Equity (%) (%)	-56.0% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-473%)	-52.4% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-449%)	-76.0% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-606%)	-79.2% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-628%)	-55.1% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-467%)	-39.5% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-364%)	-66.1% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-541%)	-26.5% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-277%)	-63.3% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-522%)	-31.7% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-311%)	-26.6% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-277%)	-26.8% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-279%)	-144.2% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1061%)	29.2% Excellent ↑ Excellent Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+95%)	214.2% Excellent ↑ Excellent Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+1328%)	-252.0% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1780%)	116.9% Excellent Excellent Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+680%)	—	—

⚖️ Is the balance sheet risky? 2 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 16, 2007 10-K ↗
Interest Coverage (x)	—	—	—	—	—	—	—	—	—	—	—	-2127.27x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-50.91x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-4.23x Weak Weak Operating income divided by interest expense Optimal: > 5x	-145.92x Weak Weak Operating income divided by interest expense Optimal: > 5x	—	—	—	—
Net Debt (USD)	$-163.08M	$-115.69M	$-114.89M	$-231.73M	$-78.23M	$-67.33M	$-13.97M	$-82.15M	$-145.37M	$-106.72M	$-33.59M	$-44.91M	$-19.67M	$0.00	$-510.22K	$-1.29M	$-8.26K	$-2.90K	$0.00

📊 What does each share earn? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 16, 2007 10-K ↗
Revenue per Share (USD)	$737.39	$566.00	$5.06	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—
Basic EPS, GAAP (USD)	$-1.09	$-1.28	$-1.89	$-2.49	$-2.23	$-1.88	—	—	—	—	—	—	—	—	—	—	—	—	—
Free Cash Flow per Share (USD)	$-940.95	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—
Book Value per Share (USD)	$1.70	$2.33	$2.28	$2.66	$3.96	$4.44	$2.37	$3.78	$1.99	$2.68	$2.14	$1.33	$0.88	$-13.82	$-0.16	$0.01	—	—	—
Tangible Book Value per Share (USD)	$1.70	$2.33	$2.28	$2.66	$3.96	$4.44	$2.37	$3.78	$1.99	$2.68	$2.14	$1.33	$0.88	$-13.82	$-0.16	$0.01	—	—	—
Basic Weighted Avg Shares (shares)	357,345	289,877	235,131	159,259	153,406	138,301	—	—	—	—	—	—	—	—	—	—	—	—	—

🏦 How resilient is the balance sheet? 2 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 16, 2007 10-K ↗
Working Capital (USD)	$304.33M	$334.68M	$197.54M	$387.63M	$418.76M	$581.23M	$277.41M	$460.98M	$139.69M	$164.54M	$102.35M	$43.31M	$17.58M	$-11.34M	$-12.83M	$478.05K	—	—	—
Total Equity (USD)	$698.58M	$710.40M	$584.61M	$499.64M	$621.66M	$656.50M	$298.97M	$466.19M	$145.48M	$166.92M	$104.02M	$44.85M	$17.60M	$-11.32M	$-12.78M	$638.09K	$-13.49K	$2.28K	$8.00K

📋 What is driving earnings? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 16, 2007 10-K ↗
Sales/Revenue/Turnover (USD)	$263.50M	$164.07M	$1.19M	—	—	—	—	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	—	—
Depreciation Expense (USD)	$12.86M	$11.26M	$11.57M	$9.31M	$3.11M	$1.14M	$1.17M	$1.00M	$1.00M	$1.00M	$1.00M	$88.22K	$7.09K	—	—	—	—	—	—
Net Income, GAAP (USD)	$-390.98M	$-372.18M	$-444.04M	$-395.89M	$-342.25M	$-259.58M	$-197.56M	$-123.58M	$-92.06M	$-52.89M	$-27.66M	$-12.03M	$-25.38M	$-3.31M	$-27.38M	$-1.61M	$-15.77K	$-58.72K	—
Operating Cash Flow (USD)	$-302.41M	$-352.98M	$-361.82M	$-292.76M	$-227.94M	$-205.13M	$-158.89M	$-101.25M	$-78.71M	$-32.67M	—	$8.63M	—	$-2.24M	$-6.88M	$-620.80K	$-14.45K	—	—

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bar_chart Data from SEC EDGAR XBRL filings

Synced 1 week ago 19 years · 67 quarters

IOVANCE BIOTHERAPEUTICS, INC.

Analytical Summary

19-Year Financial Trajectory

Bullish Indicators

Bearish Risks

Health Breakdown

Statement lens

Benchmark Lens

Signals

Percentile Rankings

Peer Comparison

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