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LIXTE BIOTECHNOLOGY HOLDINGS, INC.

LIXT

$7.29 0.00 (0.00%) at close

21 Visible periods

20 Metrics

Peer-ranked Benchmarks

Price Chart

Health

Poor

Bearish

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Analytical Summary

LIXTE BIOTECHNOLOGY HOLDINGS, INC. faces fundamental challenges with weakness in Return on Common Equity (%). The fundamentals warrant careful consideration of downside risks.

Market Cap —

Dividend Yield —

Revenue Growth —

Op. Margin —

ROIC -41.8% ↗

FCF / Share None

Trailing P/E —

Price / Book 6.6x

FCF Yield —

Debt / Equity —

info Valuation on last close. End-of-day price, Jul 2, 2026.

21-Year Financial Trajectory

Annual

Metric Value Trend Year over Year Percentile

Revenue Total top-line sales

$200.00K

— —

Net Income Profit after all expenses

$-6.08M

↓ -69.5% —

FCF / Share Free cash flow per share

$-2.24

↑ +23.1% —

trending_up

Bullish Indicators

No bullish signals detected.

warning

Bearish Risks

Return on Common Equity (%)Return on Common Equity (%) is in the bottom quartile

Health Breakdown

Returns →

Financial Health ↑

Cash Quality ↓

Financial view

Statement lens

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Annual Quarterly

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📈 Is growth accelerating? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 31, 2007 10-K ↗	FY 2006 Dec 31, 2006 10-K ↗	FY 2005 Jun 30, 2006 10-K ↗
EPS Growth YoY (%)	—	—	33.3% Excellent Excellent Year-over-year change in earnings per share Optimal: > 10%	-698.0% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—
Net Income Growth YoY (%)	-69.5% Weak ↓ Weak Declining Year-over-year change in net income	29.5% Excellent ↑ Excellent Improving Year-over-year change in net income	19.4% Good ↑ Good Improving Year-over-year change in net income	6.2% Fair ↑ Fair Improving Year-over-year change in net income	-106.1% Weak ↓ Weak Declining Year-over-year change in net income	-33.8% Weak ↓ Weak Declining Year-over-year change in net income	-14.4% Weak ↓ Weak Declining Year-over-year change in net income	-18.0% Weak ↓ Weak Declining Year-over-year change in net income	15.3% Good ↓ Good Declining Year-over-year change in net income	25.2% Excellent ↑ Excellent Improving Year-over-year change in net income	-3.1% Weak ↑ Weak Improving Year-over-year change in net income	78.6% Excellent ↑ Excellent Improving Year-over-year change in net income	-261.9% Weak ↓ Weak Declining Year-over-year change in net income	-73.1% Weak ↓ Weak Declining Year-over-year change in net income	-134.9% Weak ↓ Weak Declining Year-over-year change in net income	43.3% Excellent ↑ Excellent Improving Year-over-year change in net income	-22.0% Weak ↑ Weak Improving Year-over-year change in net income	22.9% Good Good Year-over-year change in net income	-193.3% Weak Weak Year-over-year change in net income	—	—
FCF Growth YoY (%)	—	—	23.1% Good Good Year-over-year change in free cash flow	-848.1% Weak Weak Year-over-year change in free cash flow	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—

💰 Are margins durable? 1 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 31, 2007 10-K ↗	FY 2006 Dec 31, 2006 10-K ↗	FY 2005 Jun 30, 2006 10-K ↗
FCF / Net Income (x)	0.51x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	0.88x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.84x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.73x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.62x Weak ↑ Weak Improving Free cash flow relative to reported net income Optimal: > 1x	0.65x Weak ↑ Weak Improving Free cash flow relative to reported net income Optimal: > 1x	-0.69x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	0.71x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.78x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.79x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.76x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.59x Weak ↑ Weak Improving Free cash flow relative to reported net income Optimal: > 1x	0.55x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	0.34x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	0.66x Weak Weak Free cash flow relative to reported net income Optimal: > 1x	1.06x Fair Fair Free cash flow relative to reported net income Optimal: > 1x	—	—	—	—	—

🎯 Is capital allocation efficient? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 31, 2007 10-K ↗	FY 2006 Dec 31, 2006 10-K ↗	FY 2005 Jun 30, 2006 10-K ↗
Return on Invested Capital (%)	-41.8% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-341.2% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-100.7% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-96.5% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-110.8% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-51.5% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-80.8% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-40.9% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-143.7% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-785.3% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-669.4% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-714.1% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-3754.8% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-111.5% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-1867.8% Weak Weak Return earned on debt + equity capital invested Optimal: > 10%	-40.1% Weak Weak Return earned on debt + equity capital invested Optimal: > 10%	—	—	—	—	—
Return on Capital (%) (%)	-40.1% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-311.9% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-118.1% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-113.5% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-131.9% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-62.5% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-93.2% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-49.3% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-132.3% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-492.6% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-442.6% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-445.6% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-2012.3% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-120.1% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-434.7% Weak Weak Operating profit relative to total assets Optimal: > 10%	-45.7% Weak Weak Operating profit relative to total assets Optimal: > 10%	—	—	—	—	—
Return on Common Equity (%) (%)	-62.9% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-519%)	—	-127.3% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-949%)	-122.2% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-915%)	-140.5% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1036%)	-65.1% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-534%)	-100.3% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-768%)	-51.7% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-445%)	-181.7% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1312%)	—	—	—	—	-239.9% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1700%)	—	-50.7% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-438%)	-119.2% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-895%)	—	—	-101.7% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-778%)	—

⚖️ Is the balance sheet risky? 2 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 31, 2007 10-K ↗	FY 2006 Dec 31, 2006 10-K ↗	FY 2005 Jun 30, 2006 10-K ↗
Interest Coverage (x)	-557.72x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-212.40x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-313.57x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-711.15x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-906.45x Weak Weak Operating income divided by interest expense Optimal: > 5x	-889.07x Weak Weak Operating income divided by interest expense Optimal: > 5x	—	—	—	—	—	—	-4548.19x Weak Weak Operating income divided by interest expense Optimal: > 5x	—	—	—	—	—	—	—	—
Net Debt (USD)	—	—	$-4.20M	$-5.35M	$-4.82M	$-5.07M	$-2.60M	$-4.27M	$-1.31M	$-199.93K	$-25.28K	$-44.41K	—	—	—	—	—	—	—	—	—

📊 What does each share earn? 5 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 31, 2007 10-K ↗	FY 2006 Dec 31, 2006 10-K ↗	FY 2005 Jun 30, 2006 10-K ↗
Basic EPS, GAAP (USD)	—	—	$-2.66	$-3.99	$-0.50	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—
Free Cash Flow per Share (USD)	—	—	$-2.24	$-2.92	$-0.31	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—
Book Value per Share (USD)	$1.10	$0.37	$1.78	$3.10	$0.35	$0.40	$0.22	$0.06	$0.02	$0.00	$0.01	$0.01	$0.01	$0.04	$0.00	$0.05	—	—	—	—	$0.00
Tangible Book Value per Share (USD)	$1.10	$0.37	$1.78	$3.10	$0.35	$0.40	$0.22	$0.06	$0.02	$0.00	$0.01	$0.01	$0.01	$0.04	$0.00	$0.05	—	—	—	—	$0.00
Basic Weighted Avg Shares (shares)	—	—	1.92M	1.58M	13.47M	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—

🏦 How resilient is the balance sheet? 2 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 31, 2007 10-K ↗	FY 2006 Dec 31, 2006 10-K ↗	FY 2005 Jun 30, 2006 10-K ↗
Working Capital (USD)	$3.85M	$827.22K	$3.99M	$5.17M	$4.79M	$5.01M	$2.43M	$4.12M	$995.04K	$214.76K	$312.33K	$265.86K	$236.27K	$1.49M	$79.02K	$1.74M	—	—	—	—	—
Total Equity (USD)	$9.66M	$827.22K	$3.99M	$5.17M	$4.79M	$5.01M	$2.43M	$4.13M	$995.04K	$214.76K	$312.33K	$265.86K	$236.27K	$1.49M	$79.02K	$1.74M	$1.30M	$-323.55K	$376.93K	$552.56K	$0.00

📋 What is driving earnings? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗	FY 2010 Dec 31, 2010 10-K ↗	FY 2009 Dec 31, 2009 10-K ↗	FY 2008 Dec 31, 2008 10-K ↗	FY 2007 Dec 31, 2007 10-K ↗	FY 2006 Dec 31, 2006 10-K ↗	FY 2005 Jun 30, 2006 10-K ↗
Sales/Revenue/Turnover (USD)	—	—	—	—	—	—	—	—	—	—	$200.00K	—	$0.00	$0.00	$0.00	$0.00	—	—	—	—	—
Depreciation Expense (USD)	—	—	—	—	—	—	—	—	—	—	—	—	$1.91K	$0.00	$0.00	$0.00	—	—	—	—	—
Net Income, GAAP (USD)	$-6.08M	$-3.59M	$-5.09M	$-6.31M	$-6.73M	$-3.26M	$-2.44M	$-2.13M	$-1.81M	$-2.13M	$-2.85M	$-2.77M	$-12.95M	$-3.58M	$-2.07M	$-880.25K	$-1.55M	$-1.27M	$-1.65M	$-562.08K	—
Operating Cash Flow (USD)	$-3.07M	$-3.16M	$-4.29M	$-4.61M	$-4.14M	$-2.13M	$1.67M	$-1.51M	$-1.41M	$-1.68M	$-2.18M	$-1.64M	$-7.07M	$-1.21M	$-1.36M	$-936.39K	—	—	—	—	—

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bar_chart Data from SEC EDGAR XBRL filings

Synced 1 week ago 21 years · 80 quarters

LIXTE BIOTECHNOLOGY HOLDINGS, INC.

Analytical Summary

21-Year Financial Trajectory

Bullish Indicators

Bearish Risks

Health Breakdown

Statement lens

Benchmark Lens

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