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Shuttle Pharmaceuticals Holdings, Inc.

SHPH

$4.49 ▲ +0.04 (+0.90%) at close

6 Visible periods

22 Metrics

Absolute Benchmarks

Price Chart

Health

Poor

Bearish Absolute basis

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Analytical Summary

On an absolute basis, Shuttle Pharmaceuticals Holdings, Inc. shows weak fundamentals, weighed down by Return on Invested Capital and Interest Coverage. These readings use fixed quality thresholds rather than peer benchmarks, because too few comparable companies are available to rank against.

Market Cap $7.4M

Dividend Yield —

Revenue Growth —

Op. Margin —

ROIC -417.6% ↗

FCF / Share $-5.79 ↘

Trailing P/E —

Price / Book 4.0x

FCF Yield —

Debt / Equity —

info Valuation on last close. End-of-day price, Aug 7, 2026.

6-Year Financial Trajectory

Annual

Metric Value Trend Year over Year Percentile

Net Income Profit after all expenses

$-11.72M

↓ -28.2% —

FCF / Share Free cash flow per share

$-5.79

↓ -126.8% —

info Signals below are graded against fixed quality thresholds, not peers — peer ranking needs more comparable companies.

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Bullish Indicators

No bullish signals detected.

warning

Bearish Risks

Return on Invested CapitalReturn on Invested Capital of -417.6% is weak on an absolute basis (target > 10%)
Interest CoverageInterest Coverage of -95.11x is weak on an absolute basis (target > 5x)
FCF / Net IncomeFCF / Net Income of 0.81x is caution on an absolute basis (target > 1x)

Health Breakdown

Financial Health ↑

Cash Quality ↑

Financial view

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Annual Quarterly

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📈 Is growth accelerating? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗
EPS Growth YoY (%)	-124.5% Weak ↑ Weak Improving Year-over-year change in earnings per share Optimal: > 10%	-625.0% Weak ↓ Weak Declining Year-over-year change in earnings per share Optimal: > 10%	-51.7% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	-141.7% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	—	—
Net Income Growth YoY (%)	-28.2% Weak ↑ Weak Improving Year-over-year change in net income	-38.7% Weak ↑ Weak Improving Year-over-year change in net income	-117.7% Weak Weak Year-over-year change in net income	-162.9% Weak Weak Year-over-year change in net income	—	—
FCF Growth YoY (%)	-126.8% Weak ↑ Weak Improving Year-over-year change in free cash flow	-580.1% Weak ↓ Weak Declining Year-over-year change in free cash flow	-43.3% Weak Weak Year-over-year change in free cash flow	-711.0% Weak Weak Year-over-year change in free cash flow	—	—

💰 Are margins durable? 1 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗
FCF / Net Income (x)	0.81x Caution → Caution Stable Free cash flow relative to reported net income Optimal: > 1x	0.80x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.85x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.89x Caution Caution Free cash flow relative to reported net income Optimal: > 1x	0.26x Weak Weak Free cash flow relative to reported net income Optimal: > 1x	—

🎯 Is capital allocation efficient? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗
Return on Invested Capital (%)	-417.6% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-857.4% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-114.8% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-26.3% Weak Weak Return earned on debt + equity capital invested Optimal: > 10%	89.6% Excellent Excellent Return earned on debt + equity capital invested Optimal: > 10%	—
Return on Capital (%) (%)	-113.8% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-307.1% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-99.0% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-29.5% Weak Weak Operating profit relative to total assets Optimal: > 10%	-267.5% Weak Weak Operating profit relative to total assets Optimal: > 10%	—
Return on Common Equity (%) (%)	—	—	-162.6% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1184%)	-39.4% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-363%)	70.8% Excellent Excellent Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+372%)	—

⚖️ Is the balance sheet risky? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗
Debt to Equity (x)	—	—	—	—	-0.06x Excellent Excellent Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-109%)	—
Interest Coverage (x)	-95.11x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-88.88x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-2.78x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-65.16x Weak Weak Operating income divided by interest expense Optimal: > 5x	-453.79x Weak Weak Operating income divided by interest expense Optimal: > 5x	—
Net Debt (USD)	$-334.00K	$-1.92M	$-2.58M	$-8.42M	$-413.73K	—
Debt / EBITDA (x)	—	—	—	—	-0.05x Excellent Excellent Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	—

📊 What does each share earn? 5 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗
Basic EPS, GAAP (USD)	$-7.16	$-3.19	$-0.44	$-0.29	$-0.12	—
Free Cash Flow per Share (USD)	$-5.79	$-2.55	$-0.38	$-0.26	$-0.03	—
Book Value per Share (USD)	$1.11	$0.17	$0.25	$0.56	$-0.17	—
Tangible Book Value per Share (USD)	$-3.75	$0.17	$0.25	$0.56	$-0.17	—
Basic Weighted Avg Shares (shares)	1.64M	2.87M	14.92M	10.35M	9.30M	—

🏦 How resilient is the balance sheet? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗
Working Capital (USD)	$-7.46M	$677.15K	$4.55M	$7.60M	$-1.71M	—
LT Debt (USD)	—	—	—	—	$91.02K	—
Total Equity (USD)	$2.25M	$709.15K	$4.06M	$7.68M	$-1.63M	$-1.69M

📋 What is driving earnings? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗
Depreciation Expense (USD)	—	$5.46K	$6.81K	$5.97K	$6.22K	—
Net Income, GAAP (USD)	$-11.72M	$-9.14M	$-6.59M	$-3.03M	$-1.15M	—
Operating Cash Flow (USD)	$-9.48M	$-7.33M	$-5.58M	$-2.71M	$-300.34K	—

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bar_chart Data from SEC EDGAR XBRL filings

Synced 1 week ago 6 years · 22 quarters

Shuttle Pharmaceuticals Holdings, Inc.

Analytical Summary

6-Year Financial Trajectory

Bullish Indicators

Bearish Risks

Health Breakdown

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