Xeris Biopharma Holdings, Inc.
XERSAnalytical Summary
Xeris Biopharma Holdings, Inc. faces fundamental challenges with weakness in Debt to Equity. The fundamentals warrant careful consideration of downside risks.
7-Year Financial Trajectory
AnnualBullish Indicators
- No bullish signals detected.
Bearish Risks
- Debt to EquityDebt to Equity is concerning (bottom quartile)
Health Breakdown
Statement lens
Choose the reporting cadence, isolate a period range, or search directly for a metric.
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Revenue Growth YoY (%) |
43.7%
Excellent
↓
Excellent
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+446%)
|
23.9%
Excellent
↓
Excellent
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+199%)
|
48.7%
Excellent
↓
Excellent
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+508%)
|
122.3%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+1429%)
|
142.7%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+1683%)
|
— | — |
| EPS Growth YoY (%) |
100.0%
Excellent
↑
Excellent
Improving
Year-over-year change in earnings per share
Optimal:
> 10%
|
17.8%
Good
↓
Good
Declining
Year-over-year change in earnings per share
Optimal:
> 10%
|
35.7%
Excellent
Excellent
Year-over-year change in earnings per share
Optimal:
> 10%
|
54.8%
Excellent
Excellent
Year-over-year change in earnings per share
Optimal:
> 10%
|
— | — | — |
| Net Income Growth YoY (%) | N/M |
11.9%
Fair
↑
Fair
Improving
Year-over-year change in net income |
34.2%
Excellent
↑
Excellent
Improving
Year-over-year change in net income |
22.9%
Good
Good
Year-over-year change in net income |
-34.7%
Weak
Weak
Year-over-year change in net income |
— | — |
| FCF Growth YoY (%) | N/M |
26.2%
Excellent
↓
Excellent
Declining
Year-over-year change in free cash flow |
55.0%
Excellent
Excellent
Year-over-year change in free cash flow |
37.2%
Excellent
Excellent
Year-over-year change in free cash flow |
— | — | — |
| Revenue CAGR 3Y (%) |
38.3%
Excellent
↓
Excellent
Declining
Compound annual revenue growth over 3 years |
60.0%
Excellent
Excellent
Compound annual revenue growth over 3 years |
100.2%
Excellent
Excellent
Compound annual revenue growth over 3 years |
— | — | — | — |
| Revenue CAGR 5Y (%) |
70.2%
Excellent
Excellent
Compound annual revenue growth over 5 years |
— | — | — | — | — | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Operating Margin (%) (%) |
8.5%
Caution
↑
Caution
Improving
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-43%)
|
-16.6%
Weak
↑
Weak
Improving
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-210%)
|
-26.8%
Weak
↑
Weak
Improving
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-279%)
|
-74.3%
Weak
↑
Weak
Improving
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-595%)
|
-232.2%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1648%)
|
-408.8%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-2826%)
|
— |
| Effective Tax Rate (%) (%) |
0.0%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
4.0%
Excellent
↑
Excellent
Improving
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
2.0%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
1.5%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
— | — | — |
| Profit Margin (%) (%) |
0.2%
Weak
↑
Weak
Improving
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-98%)
|
-27.0%
Weak
↑
Weak
Improving
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-325%)
|
-38.0%
Weak
↑
Weak
Improving
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-417%)
|
-85.9%
Weak
↑
Weak
Improving
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-816%)
|
-247.5%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-2162%)
|
-446.0%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-3817%)
|
— |
| FCF Margin (%) (%) |
9.8%
Caution
↑
Caution
Improving
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-18.2%
Weak
↑
Weak
Improving
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-28.7%
Weak
↑
Weak
Improving
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-93.3%
Weak
↑
Weak
Improving
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-192.6%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-396.1%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
— |
| FCF / Net Income (x) |
51.67x
Excellent
↑
Excellent
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.67x
Weak
↓
Weak
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.76x
Caution
↓
Caution
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.09x
Fair
↑
Fair
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.78x
Caution
Caution
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.89x
Caution
Caution
Free cash flow relative to reported net income
Optimal:
> 1x
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Return on Invested Capital (%) |
10.6%
Good
↑
Good
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-16.0%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-23.4%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-34.8%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-49.6%
Weak
Weak
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-54.6%
Weak
Weak
Return earned on debt + equity capital invested
Optimal:
> 10%
|
— |
| Return on Capital (%) (%) |
6.5%
Caution
↑
Caution
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-10.4%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-13.6%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-23.8%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-37.8%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
-52.5%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
— |
| Return on Common Equity (%) (%) |
4.0%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-73%)
|
185.2%
Excellent
↑
Excellent
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Above avg (+1134%)
|
— |
-209.5%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-1497%)
|
-128.9%
Weak
Weak
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-959%)
|
-270.0%
Weak
Weak
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-1900%)
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Debt to Equity (x) |
16.10x
Weak
↑
Weak
Improving
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Above avg (+2583%)
|
-7.84x
Excellent
→
Excellent
Stable
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-1406%)
|
-28.15x
Excellent
↓
Excellent
Declining
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-4792%)
|
4.14x
Weak
↑
Weak
Improving
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Above avg (+590%)
|
0.92x
Fair
Fair
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Above avg (+54%)
|
2.58x
Weak
Weak
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Above avg (+330%)
|
— |
| Interest Coverage (x) |
0.92x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-1.25x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-1.59x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-5.81x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-16.04x
Weak
Weak
Operating income divided by interest expense
Optimal:
> 5x
|
-7.84x
Weak
Weak
Operating income divided by interest expense
Optimal:
> 5x
|
— |
| Net Debt (USD) | $109.29M | $160.49M | $123.48M | $65.11M | $20.80M | $49.42M | $-19.52M |
| Debt / EBITDA (x) |
8.41x
Weak
↑
Weak
Improving
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-7.16x
Excellent
↓
Excellent
Declining
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-4.49x
Excellent
↓
Excellent
Declining
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-2.32x
Excellent
↓
Excellent
Declining
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-0.77x
Excellent
Excellent
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-1.06x
Excellent
Excellent
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Working Capital (USD) | $130.74M | $67.22M | $61.07M | $113.20M | $63.56M | $124.00M | — |
| LT Debt (USD) | $220.34M | $232.11M | $190.93M | $187.07M | $88.07M | $87.02M | — |
| Total Equity (USD) | $13.69M | $-29.61M | $-6.78M | $45.19M | $95.23M | $33.76M | $14.44M |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Sales/Revenue/Turnover (USD) | $291.85M | $203.07M | $163.91M | $110.25M | $49.59M | $20.43M | — |
| Depreciation Expense (USD) | $1.31M | $1.23M | $1.49M | $1.40M | $1.33M | $1.47M | — |
| Net Income, GAAP (USD) | $554.00K | $-54.84M | $-62.26M | $-94.66M | $-122.72M | $-91.14M | — |
| Operating Cash Flow (USD) | $28.63M | $-36.98M | $-47.02M | $-102.89M | $-95.53M | $-80.56M | — |
Secondary lens
Benchmark Lens
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Open lens
Benchmark Lens
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Signals
Key bullish and bearish indicators for XERS
No bullish signals detected
Debt to Equity is concerning (bottom quartile)
Percentile Rankings
How XERS compares to all companies
Peer Comparison
XERS vs similar peers
Compare XERS with peers
Stack XERS against similar companies across every metric on this page.
north_east Open comparisonbar_chart Data from SEC EDGAR XBRL filings
Synced 1 week ago 7 years · 26 quarters