Xilio Therapeutics, Inc.
XLOAnalytical Summary
Xilio Therapeutics, Inc. faces fundamental challenges with weakness in Return on Common Equity (%) and Profit Margin (%). The fundamentals warrant careful consideration of downside risks.
7-Year Financial Trajectory
AnnualBullish Indicators
- No bullish signals detected.
Bearish Risks
- Operating Margin (%)Operating Margin (%) is in the bottom quartile
- Profit Margin (%)Profit Margin (%) is in the bottom quartile
- Return on Common Equity (%)Return on Common Equity (%) is in the bottom quartile
Health Breakdown
Statement lens
Choose the reporting cadence, isolate a period range, or search directly for a metric.
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Revenue Growth YoY (%) |
589.9%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+7274%)
|
— | — | — | — | — | — |
| EPS Growth YoY (%) |
72.5%
Excellent
↑
Excellent
Improving
Year-over-year change in earnings per share
Optimal:
> 10%
|
-448.2%
Weak
↓
Weak
Declining
Year-over-year change in earnings per share
Optimal:
> 10%
|
13.7%
Fair
↓
Fair
Declining
Year-over-year change in earnings per share
Optimal:
> 10%
|
76.2%
Excellent
Excellent
Year-over-year change in earnings per share
Optimal:
> 10%
|
87.2%
Excellent
Excellent
Year-over-year change in earnings per share
Optimal:
> 10%
|
— | — |
| Net Income Growth YoY (%) |
39.8%
Excellent
↑
Excellent
Improving
Year-over-year change in net income |
23.8%
Good
↑
Good
Improving
Year-over-year change in net income |
13.4%
Fair
↑
Fair
Improving
Year-over-year change in net income |
-16.4%
Weak
Weak
Year-over-year change in net income |
-37.3%
Weak
Weak
Year-over-year change in net income |
— | — |
| FCF Growth YoY (%) |
86.3%
Excellent
↑
Excellent
Improving
Year-over-year change in free cash flow |
-91.7%
Weak
↓
Weak
Declining
Year-over-year change in free cash flow |
11.3%
Fair
↓
Fair
Declining
Year-over-year change in free cash flow |
80.6%
Excellent
Excellent
Year-over-year change in free cash flow |
80.0%
Excellent
Excellent
Year-over-year change in free cash flow |
— | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Operating Margin (%) (%) |
-95.9%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-739%)
|
— | — | — | — | — | — |
| Effective Tax Rate (%) (%) |
0.0%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
0.0%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
— | — | — | — | — |
| Profit Margin (%) (%) |
-80.1%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-767%)
|
— | — | — | — | — | — |
| FCF Margin (%) (%) |
-12.6%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-290.3%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
— | — | — | — | — |
| FCF / Net Income (x) |
0.16x
Weak
↓
Weak
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.32x
Weak
↓
Weak
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.90x
Caution
→
Caution
Stable
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.88x
Caution
→
Caution
Stable
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.08x
Fair
Fair
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.69x
Weak
Weak
Free cash flow relative to reported net income
Optimal:
> 1x
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Return on Invested Capital (%) |
-119.0%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-344.3%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-169.8%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-66.7%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-32.0%
Weak
Weak
Return earned on debt + equity capital invested
Optimal:
> 10%
|
51.8%
Excellent
Excellent
Return earned on debt + equity capital invested
Optimal:
> 10%
|
— |
| Return on Capital (%) (%) |
-27.1%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-85.2%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-129.9%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-64.1%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-34.4%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
-150.2%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
— |
| Return on Common Equity (%) (%) |
-99.3%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-762%)
|
— |
-207.5%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-1483%)
|
-83.5%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-657%)
|
-40.9%
Weak
Weak
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-373%)
|
66.3%
Excellent
Excellent
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Above avg (+342%)
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Interest Coverage (x) | — |
-977.13x
Weak
↓
Weak
Declining
Operating income divided by interest expense
Optimal:
> 5x
|
-138.10x
Weak
→
Weak
Stable
Operating income divided by interest expense
Optimal:
> 5x
|
-160.63x
Weak
↓
Weak
Declining
Operating income divided by interest expense
Optimal:
> 5x
|
-152.53x
Weak
Weak
Operating income divided by interest expense
Optimal:
> 5x
|
-101.80x
Weak
Weak
Operating income divided by interest expense
Optimal:
> 5x
|
— |
| Net Debt (USD) | $-137.53M | $-55.29M | $-44.70M | $-120.39M | $-198.05M | $-19.24M | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Working Capital (USD) | $88.75M | $32.97M | $32.17M | $103.38M | $189.74M | $-1.56M | — |
| Total Equity (USD) | $35.27M | $17.60M | $36.83M | $105.65M | $185.43M | $-83.29M | $-29.52M |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Sales/Revenue/Turnover (USD) | $43.77M | $6.34M | — | — | — | — | — |
| Depreciation Expense (USD) | $1.54M | $1.64M | $1.90M | $1.85M | $1.50M | $1.06M | — |
| Net Income, GAAP (USD) | $-35.04M | $-58.24M | $-76.40M | $-88.22M | $-75.80M | $-55.22M | — |
| Operating Cash Flow (USD) | $-4.99M | $-18.38M | $-68.62M | $-75.72M | $-80.75M | $-36.09M | — |
Secondary lens
Benchmark Lens
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Open lens
Benchmark Lens
Compare XLO against peers after checking the statement evidence.
Signals
Key bullish and bearish indicators for XLO
No bullish signals detected
Operating Margin (%) is in the bottom quartile
Profit Margin (%) is in the bottom quartile
Return on Common Equity (%) is in the bottom quartile
Percentile Rankings
How XLO compares to all companies
Peer Comparison
XLO vs similar peers
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Stack XLO against similar companies across every metric on this page.
north_east Open comparisonbar_chart Data from SEC EDGAR XBRL filings
Synced 1 week ago 7 years · 26 quarters