Alector, Inc.
ALECAnalytical Summary
Alector, Inc. shows mixed fundamentals. Consider comparing against peers in the Healthcare sector before making investment decisions.
10-Year Financial Trajectory
AnnualHealth Breakdown
Statement lens
Choose the reporting cadence, isolate a period range, or search directly for a metric.
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue Growth YoY (%) |
-79.1%
Weak
↓
Weak
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Below avg (-1088%)
|
3.6%
Caution
↓
Caution
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Below avg (-55%)
|
-27.3%
Weak
↓
Weak
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Below avg (-442%)
|
-35.5%
Weak
↓
Weak
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Below avg (-543%)
|
881.5%
Excellent
↑
Excellent
Improving
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+10919%)
|
-0.6%
Weak
↓
Weak
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Below avg (-107%)
|
-23.3%
Weak
Weak
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Below avg (-392%)
|
641.0%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+7913%)
|
— | — |
| EPS Growth YoY (%) |
-13.0%
Weak
↑
Weak
Improving
Year-over-year change in earnings per share
Optimal:
> 10%
|
21.2%
Good
↑
Good
Improving
Year-over-year change in earnings per share
Optimal:
> 10%
|
3.7%
Caution
Caution
Year-over-year change in earnings per share
Optimal:
> 10%
|
-260.0%
Weak
Weak
Year-over-year change in earnings per share
Optimal:
> 10%
|
— | — | — | — | — | — |
| Net Income Growth YoY (%) |
-20.1%
Weak
↑
Weak
Improving
Year-over-year change in net income |
8.7%
Fair
↑
Fair
Improving
Year-over-year change in net income |
2.2%
Caution
↑
Caution
Improving
Year-over-year change in net income |
-267.0%
Weak
↓
Weak
Declining
Year-over-year change in net income |
80.9%
Excellent
↑
Excellent
Improving
Year-over-year change in net income |
-80.5%
Weak
→
Weak
Stable
Year-over-year change in net income |
-101.7%
Weak
Weak
Year-over-year change in net income |
-60.9%
Weak
Weak
Year-over-year change in net income |
— | — |
| FCF Growth YoY (%) |
25.3%
Excellent
↑
Excellent
Improving
Year-over-year change in free cash flow |
-7.4%
Weak
Weak
Year-over-year change in free cash flow |
-651.5%
Weak
Weak
Year-over-year change in free cash flow |
N/M | — | — | — | — | — | — |
| Revenue CAGR 3Y (%) |
-46.0%
Weak
↓
Weak
Declining
Compound annual revenue growth over 3 years |
-21.4%
Weak
↓
Weak
Declining
Compound annual revenue growth over 3 years |
66.3%
Excellent
↓
Excellent
Declining
Compound annual revenue growth over 3 years |
84.7%
Excellent
→
Excellent
Stable
Compound annual revenue growth over 3 years |
95.6%
Excellent
Excellent
Compound annual revenue growth over 3 years |
78.1%
Excellent
Excellent
Compound annual revenue growth over 3 years |
— | — | — | — |
| Revenue CAGR 5Y (%) |
-0.1%
Weak
↓
Weak
Declining
Compound annual revenue growth over 5 years |
36.5%
Excellent
↓
Excellent
Declining
Compound annual revenue growth over 5 years |
28.5%
Excellent
Excellent
Compound annual revenue growth over 5 years |
104.5%
Excellent
Excellent
Compound annual revenue growth over 5 years |
— | — | — | — | — | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin (%) (%) | — |
-144.2%
Weak
↓
Weak
Declining
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1061%)
|
-156.3%
Weak
↓
Weak
Declining
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1142%)
|
-103.2%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-788%)
|
-18.0%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-220%)
|
— | — |
-207.0%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1480%)
|
— | — |
| Effective Tax Rate (%) (%) |
-0.1%
Excellent
↑
Excellent
Improving
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-0.1%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-4.2%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
— | — | — | — | — | — | — |
| Profit Margin (%) (%) | — |
-118.4%
Weak
↓
Weak
Declining
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1087%)
|
-134.3%
Weak
↓
Weak
Declining
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1219%)
|
-99.8%
Weak
↑
Weak
Improving
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-931%)
|
-17.5%
Weak
↑
Weak
Improving
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-246%)
|
— |
-496.7%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-4239%)
|
-188.8%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1673%)
|
— | — |
| FCF Margin (%) (%) | — |
-229.9%
Weak
↓
Weak
Declining
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-192.1%
Weak
↓
Weak
Declining
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-18.3%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
142.6%
Excellent
Excellent
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
— | — |
453.7%
Excellent
Excellent
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-497.2%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
— |
| FCF / Net Income (x) |
1.29x
Good
↑
Good
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.94x
Excellent
↑
Excellent
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.43x
Good
↑
Good
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.18x
Weak
↑
Weak
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
-8.13x
Weak
↓
Weak
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.90x
Caution
↑
Caution
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.09x
Fair
↑
Fair
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
-2.40x
Weak
Weak
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.57x
Weak
Weak
Free cash flow relative to reported net income
Optimal:
> 1x
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Return on Invested Capital (%) |
-384.2%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-106.6%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-117.8%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-50.8%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-9.8%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-57.6%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-46.4%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
46.5%
Excellent
Excellent
Return earned on debt + equity capital invested
Optimal:
> 10%
|
49.6%
Excellent
Excellent
Return earned on debt + equity capital invested
Optimal:
> 10%
|
— |
| Return on Capital (%) (%) |
-53.2%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-31.0%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-24.4%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-17.5%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-4.6%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-40.0%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-27.1%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
-18.6%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
— | — |
| Return on Common Equity (%) (%) | — |
-93.9%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-726%)
|
-97.2%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-748%)
|
-62.2%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-514%)
|
-12.1%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-181%)
|
-71.1%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-574%)
|
-54.1%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-461%)
|
53.6%
Excellent
Excellent
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Above avg (+258%)
|
62.4%
Excellent
Excellent
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Above avg (+316%)
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Debt to Equity (x) |
0.34x
Good
↑
Good
Improving
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-44%)
|
0.07x
Excellent
Excellent
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-88%)
|
0.00x
Excellent
Excellent
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-100%)
|
— | — | — | — | — | — | — |
| Interest Coverage (x) |
-182.46x
Weak
Weak
Operating income divided by interest expense
Optimal:
> 5x
|
— | — | — | — | — | — | — | — | — |
| Net Debt (USD) | $-55.44M | $-23.63M | $-74.56M | $-154.32M | $-329.15M | $-49.97M | $-89.64M | $-65.47M | $-32.45M | — |
| Debt / EBITDA (x) |
-0.07x
Excellent
↓
Excellent
Declining
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-0.06x
Excellent
Excellent
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
0.00x
Excellent
Excellent
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
— | — | — | — | — | — | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Working Capital (USD) | $196.95M | $299.76M | $387.86M | $632.63M | $610.16M | $353.42M | $295.47M | $245.23M | — | — |
| LT Debt (USD) | $10.00M | $9.39M | $0.00 | — | — | — | — | — | — | — |
| Total Equity (USD) | $30.65M | $126.80M | $134.16M | $214.44M | $300.72M | $267.53M | $194.74M | $-97.40M | $-52.03M | $-24.91M |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue/Turnover (USD) | $21.05M | $100.56M | $97.10M | $133.62M | $207.09M | $21.10M | $21.22M | $27.68M | $3.73M | — |
| Net Income, GAAP (USD) | $-142.93M | $-119.05M | $-130.39M | $-133.31M | $-36.33M | $-190.23M | $-105.39M | $-52.25M | $-32.48M | — |
| Operating Cash Flow (USD) | $-184.03M | $-229.91M | $-184.16M | $-20.33M | $298.55M | $-166.73M | $-99.31M | $127.46M | $-17.77M | — |
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Synced 1 week ago 10 years · 35 quarters