BICYCLE THERAPEUTICS PLC
BCYCAnalytical Summary
BICYCLE THERAPEUTICS PLC faces fundamental challenges with weakness in Return on Common Equity (%). The fundamentals warrant careful consideration of downside risks.
10-Year Financial Trajectory
AnnualBullish Indicators
- No bullish signals detected.
Bearish Risks
- Operating Margin (%)Operating Margin (%) is in the bottom quartile
- Profit Margin (%)Profit Margin (%) is in the bottom quartile
- Return on Common Equity (%)Return on Common Equity (%) is in the bottom quartile
Health Breakdown
Dividend History
Dividend / share · sourced from SEC filingsStatement lens
Choose the reporting cadence, isolate a period range, or search directly for a metric.
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue Growth YoY (%) |
105.8%
Excellent
↑
Excellent
Improving
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+1222%)
|
30.8%
Excellent
↓
Excellent
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+285%)
|
86.5%
Excellent
↑
Excellent
Improving
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+981%)
|
23.6%
Excellent
↓
Excellent
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+196%)
|
12.6%
Good
↓
Good
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+57%)
|
-24.7%
Weak
↓
Weak
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Below avg (-409%)
|
93.4%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+1067%)
|
246.4%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+2980%)
|
— | — |
| EPS Growth YoY (%) |
-9.0%
Weak
↑
Weak
Improving
Year-over-year change in earnings per share
Optimal:
> 10%
|
42.9%
Excellent
↑
Excellent
Improving
Year-over-year change in earnings per share
Optimal:
> 10%
|
-33.7%
Weak
↓
Weak
Declining
Year-over-year change in earnings per share
Optimal:
> 10%
|
-42.3%
Weak
Weak
Year-over-year change in earnings per share
Optimal:
> 10%
|
-0.4%
Weak
Weak
Year-over-year change in earnings per share
Optimal:
> 10%
|
— | — | — | — | — |
| Net Income Growth YoY (%) |
-29.5%
Weak
↑
Weak
Improving
Year-over-year change in net income |
6.4%
Fair
↑
Fair
Improving
Year-over-year change in net income |
-60.3%
Weak
↓
Weak
Declining
Year-over-year change in net income |
-68.7%
Weak
↓
Weak
Declining
Year-over-year change in net income |
-31.0%
Weak
↑
Weak
Improving
Year-over-year change in net income |
-66.7%
Weak
↓
Weak
Declining
Year-over-year change in net income |
-40.1%
Weak
Weak
Year-over-year change in net income |
-34.4%
Weak
Weak
Year-over-year change in net income |
— | — |
| FCF Growth YoY (%) |
-27.6%
Weak
↑
Weak
Improving
Year-over-year change in free cash flow |
-59.7%
Weak
↑
Weak
Improving
Year-over-year change in free cash flow |
49.6%
Excellent
↑
Excellent
Improving
Year-over-year change in free cash flow |
-427.8%
Weak
Weak
Year-over-year change in free cash flow |
32.3%
Excellent
Excellent
Year-over-year change in free cash flow |
— | — | — | — | — |
| Revenue CAGR 3Y (%) |
71.2%
Excellent
↑
Excellent
Improving
Compound annual revenue growth over 3 years |
44.5%
Excellent
↑
Excellent
Improving
Compound annual revenue growth over 3 years |
37.4%
Excellent
↑
Excellent
Improving
Compound annual revenue growth over 3 years |
1.6%
Weak
↓
Weak
Declining
Compound annual revenue growth over 3 years |
17.9%
Excellent
Excellent
Compound annual revenue growth over 3 years |
71.5%
Excellent
Excellent
Compound annual revenue growth over 3 years |
— | — | — | — |
| Revenue CAGR 5Y (%) |
47.5%
Excellent
↑
Excellent
Improving
Compound annual revenue growth over 5 years |
20.6%
Excellent
↓
Excellent
Declining
Compound annual revenue growth over 5 years |
30.5%
Excellent
Excellent
Compound annual revenue growth over 5 years |
47.7%
Excellent
Excellent
Compound annual revenue growth over 5 years |
— | — | — | — | — | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin (%) (%) |
-340.4%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-2369%)
|
— | — | — | — | — |
-190.6%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1370%)
|
-304.7%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-2132%)
|
— | — |
| Effective Tax Rate (%) (%) |
-0.1%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
2.7%
Excellent
↑
Excellent
Improving
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-0.8%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
1.3%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
2.4%
Excellent
↑
Excellent
Improving
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
1.4%
Excellent
↑
Excellent
Improving
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
0.8%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
1.8%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
0.1%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
— |
| Profit Margin (%) (%) |
-301.7%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-2614%)
|
-479.2%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-4093%)
|
— | — | — |
-491.0%
Weak
↓
Weak
Declining
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-4191%)
|
-221.8%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1948%)
|
-306.1%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-2651%)
|
— | — |
| FCF Margin (%) (%) |
-347.2%
Weak
→
Weak
Stable
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-470.5%
Weak
↓
Weak
Declining
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-235.6%
Weak
↓
Weak
Declining
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
— |
-143.8%
Weak
↑
Weak
Improving
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-182.8%
Weak
↑
Weak
Improving
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-218.6%
Weak
↑
Weak
Improving
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-382.1%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-122.7%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
— |
| FCF / Net Income (x) |
1.15x
Fair
↑
Fair
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.98x
Caution
↑
Caution
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.35x
Weak
↓
Weak
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.93x
Caution
↑
Caution
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.25x
Weak
↓
Weak
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.37x
Weak
↓
Weak
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.99x
Caution
↑
Caution
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.25x
Good
Good
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.16x
Weak
Weak
Free cash flow relative to reported net income
Optimal:
> 1x
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Return on Invested Capital (%) |
-40.5%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-25.7%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-47.7%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-38.2%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-17.0%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-46.6%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-28.0%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
30.6%
Excellent
Excellent
Return earned on debt + equity capital invested
Optimal:
> 10%
|
34.3%
Excellent
Excellent
Return earned on debt + equity capital invested
Optimal:
> 10%
|
— |
| Return on Capital (%) (%) |
-34.4%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-21.9%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-31.9%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-28.4%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-13.7%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-32.2%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-23.9%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
-26.6%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
— | — |
| Return on Common Equity (%) (%) |
-35.9%
Weak
→
Weak
Stable
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-339%)
|
-21.3%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-242%)
|
-48.7%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-425%)
|
-41.6%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-378%)
|
-19.3%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-229%)
|
-53.4%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-456%)
|
-32.8%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-319%)
|
31.3%
Excellent
Excellent
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Above avg (+109%)
|
34.5%
Excellent
Excellent
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Above avg (+130%)
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Debt to Equity (x) | — | — |
0.08x
Excellent
↓
Excellent
Declining
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-86%)
|
0.11x
Excellent
↓
Excellent
Declining
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-81%)
|
0.09x
Excellent
Excellent
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-86%)
|
0.15x
Excellent
Excellent
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-75%)
|
— | — | — | — |
| Interest Coverage (x) | — |
-152.86x
Weak
↓
Weak
Declining
Operating income divided by interest expense
Optimal:
> 5x
|
-58.21x
Weak
→
Weak
Stable
Operating income divided by interest expense
Optimal:
> 5x
|
-34.88x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-21.99x
Weak
Weak
Operating income divided by interest expense
Optimal:
> 5x
|
-113.70x
Weak
Weak
Operating income divided by interest expense
Optimal:
> 5x
|
— | — | — | — |
| Net Debt (USD) | $-628.11M | $-879.52M | $-495.73M | $-308.84M | $-408.81M | $14.51M | $0.00 | $0.00 | — | — |
| Debt / EBITDA (x) | — | — |
-0.17x
Excellent
↑
Excellent
Improving
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-0.27x
Excellent
↑
Excellent
Improving
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-0.47x
Excellent
Excellent
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-0.29x
Excellent
Excellent
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
— | — | — | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Working Capital (USD) | $625.90M | $861.38M | $492.33M | $316.04M | $422.32M | $132.59M | $95.33M | $67.84M | — | — |
| LT Debt (USD) | — | — | $30.70M | $30.32M | $29.87M | $14.51M | — | — | — | — |
| Total Equity (USD) | $609.98M | $793.06M | $370.93M | $270.78M | $346.25M | $95.46M | $93.20M | $-69.83M | $-47.18M | $-33.80M |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue/Turnover (USD) | $72.59M | $35.27M | $26.98M | $14.46M | $11.70M | $10.39M | $13.80M | $7.14M | $2.06M | — |
| Depreciation Expense (USD) | $6.42M | $7.17M | $6.55M | $3.69M | $1.41M | $1.28M | $960.00K | $712.00K | $332.00K | — |
| Net Income, GAAP (USD) | $-218.96M | $-169.03M | $-180.66M | $-112.72M | $-66.82M | $-51.01M | $-30.61M | $-21.85M | $-16.26M | — |
| Operating Cash Flow (USD) | $-249.68M | $-164.72M | $-60.63M | $-86.11M | $-14.79M | $-17.79M | $-28.61M | $-26.08M | $-1.42M | — |
Secondary lens
Benchmark Lens
Compare BCYC against peers after checking the statement evidence.
Open lens
Benchmark Lens
Compare BCYC against peers after checking the statement evidence.
Signals
Key bullish and bearish indicators for BCYC
No bullish signals detected
Operating Margin (%) is in the bottom quartile
Profit Margin (%) is in the bottom quartile
Return on Common Equity (%) is in the bottom quartile
Percentile Rankings
How BCYC compares to all companies
Peer Comparison
BCYC vs similar peers
Compare BCYC with peers
Stack BCYC against similar companies across every metric on this page.
north_east Open comparisonbar_chart Data from SEC EDGAR XBRL filings
Synced 1 week ago 10 years · 36 quarters