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Krystal Biotech, Inc.

KRYS

$300.17 ▼ -10.60 (-3.41%) at close

9 Visible periods

29 Metrics

Peer-ranked Benchmarks

Price Chart

Health

Excellent

Bullish

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Analytical Summary

Krystal Biotech, Inc. shows strong fundamentals with top-quartile Return on Common Equity (%) and Profit Margin (%). The company's metrics support a bullish outlook for growth-oriented investors.

Market Cap $8.7B

Dividend Yield —

Revenue Growth 33.9% ↘

Op. Margin 41.5% ↗

ROIC 14.3% ↗

FCF / Share $6.53 ↗

Trailing P/E 42.4x

Price / Book 7.2x

FCF Yield 2.2%

Debt / Equity —

info Valuation on last close. End-of-day price, Nov 5, 2026.

9-Year Financial Trajectory

Annual

Metric Value Trend Year over Year Percentile

Revenue Total top-line sales

$389.13M

↑ +33.9% —

Net Income Profit after all expenses

$204.83M

↑ +129.7% —

Operating Margin Operating profit as % of sales

41.5%

↑ +83.2% 94th

FCF / Share Free cash flow per share

$6.53

↑ +56.6% —

trending_up

Bullish Indicators

Operating Margin (%)Operating Margin (%) is in the top quartile
Profit Margin (%)Profit Margin (%) is in the top quartile
Return on Common Equity (%)Return on Common Equity (%) is in the top quartile

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Bearish Risks

No bearish risks detected.

Health Breakdown

Profitability ↑

Returns

Cash Quality ↓

Financial view

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📈 Is growth accelerating? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2017 10-K ↗	FY 2017 Dec 31, 2016 10-K ↗
Revenue Growth YoY (%)	33.9% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+324%)	473.0% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+5813%)	—	—	—	—	—	—	—
EPS Growth YoY (%)	126.9% Excellent ↓ Excellent Declining Year-over-year change in earnings per share Optimal: > 10%	680.0% Excellent ↑ Excellent Improving Year-over-year change in earnings per share Optimal: > 10%	N/M	-75.4% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	-83.0% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	—	—	—	—
Net Income Growth YoY (%)	129.7% Excellent ↓ Excellent Declining Year-over-year change in net income	715.6% Excellent ↑ Excellent Improving Year-over-year change in net income	N/M	-101.2% Weak ↑ Weak Improving Year-over-year change in net income	-116.3% Weak ↑ Weak Improving Year-over-year change in net income	-68.5% Weak ↑ Weak Improving Year-over-year change in net income	-141.0% Weak Weak Year-over-year change in net income	-588.7% Weak Weak Year-over-year change in net income	—
FCF Growth YoY (%)	56.6% Excellent ↑ Excellent Improving Year-over-year change in free cash flow	N/M	38.5% Excellent ↑ Excellent Improving Year-over-year change in free cash flow	-15.0% Weak Weak Year-over-year change in free cash flow	-140.5% Weak Weak Year-over-year change in free cash flow	—	—	—	—

💰 Are margins durable? 5 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2017 10-K ↗	FY 2017 Dec 31, 2016 10-K ↗
Operating Margin (%) (%)	41.5% Excellent ↑ Excellent Improving Operating income as a percentage of revenue Optimal: > 15% vs Sector: Above avg (+176%)	22.6% Good Good Operating income as a percentage of revenue Optimal: > 15% vs Sector: Above avg (+51%)	-216.4% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1543%)	—	—	—	—	—	—
Effective Tax Rate (%) (%)	-8.1% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	6.5% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	15.2% Good Good Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.0% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	—	—	—	—	—
Profit Margin (%) (%)	52.6% Excellent ↑ Excellent Improving Net income as a percentage of revenue Optimal: > 15% vs Sector: Above avg (+339%)	30.7% Excellent Excellent Net income as a percentage of revenue Optimal: > 15% vs Sector: Above avg (+156%)	21.6% Excellent Excellent Net income as a percentage of revenue Optimal: > 15% vs Sector: Above avg (+80%)	—	—	—	—	—	—
FCF Margin (%) (%)	48.5% Excellent ↑ Excellent Improving Free cash flow as a percentage of revenue Optimal: > 10%	41.0% Excellent Excellent Free cash flow as a percentage of revenue Optimal: > 10%	-198.4% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	—	—	—	—	—	—
FCF / Net Income (x)	0.92x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	1.34x Good ↑ Good Improving Free cash flow relative to reported net income Optimal: > 1x	-9.20x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	1.10x Fair ↓ Fair Declining Free cash flow relative to reported net income Optimal: > 1x	1.67x Excellent ↑ Excellent Improving Free cash flow relative to reported net income Optimal: > 1x	1.27x Good Good Free cash flow relative to reported net income Optimal: > 1x	1.31x Good Good Free cash flow relative to reported net income Optimal: > 1x	—	—

🎯 Is capital allocation efficient? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2017 10-K ↗	FY 2017 Dec 31, 2016 10-K ↗
Return on Invested Capital (%)	14.3% Good ↑ Good Improving Return earned on debt + equity capital invested Optimal: > 10%	6.5% Caution ↑ Caution Improving Return earned on debt + equity capital invested Optimal: > 10%	-11.9% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-27.8% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-9.1% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-8.9% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-15.4% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-7.0% Weak Weak Return earned on debt + equity capital invested Optimal: > 10%	-312.4% Weak Weak Return earned on debt + equity capital invested Optimal: > 10%
Return on Capital (%) (%)	12.1% Good ↑ Good Improving Operating profit relative to total assets Optimal: > 10%	6.2% Caution ↑ Caution Improving Operating profit relative to total assets Optimal: > 10%	-13.4% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-26.0% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-10.9% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-10.6% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-10.6% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-9.5% Weak Weak Operating profit relative to total assets Optimal: > 10%	-52.4% Weak Weak Operating profit relative to total assets Optimal: > 10%
Return on Common Equity (%) (%)	16.8% Good ↑ Good Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+12%)	9.4% Caution ↑ Caution Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-37%)	1.4% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-91%)	-26.8% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-279%)	-11.7% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-178%)	-11.0% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-173%)	-16.9% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-212%)	-16.0% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-207%)	—

⚖️ Is the balance sheet risky? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2017 10-K ↗	FY 2017 Dec 31, 2016 10-K ↗
Debt to Equity (x)	—	—	—	—	—	—	—	0.09x Excellent Excellent Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-86%)	—
Interest Coverage (x)	—	—	—	—	-45.76x Weak Weak Operating income divided by interest expense Optimal: > 5x	—	—	—	—
Net Debt (USD)	$-496.30M	$-344.87M	$-358.33M	$-161.90M	$-341.25M	$-268.27M	$-187.51M	$-45.34M	$-1.92M
Debt / EBITDA (x)	—	—	—	—	—	—	—	-0.90x Excellent Excellent Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	—

📊 What does each share earn? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2017 10-K ↗	FY 2017 Dec 31, 2016 10-K ↗
Revenue per Share (USD)	$13.44	$10.16	$1.87	$0.00	—	—	—	—	—
Basic EPS, GAAP (USD)	$7.08	$3.12	$0.40	$-5.49	$-3.13	$-1.71	—	—	—
Free Cash Flow per Share (USD)	$6.53	$4.17	$-3.70	$-6.02	$-5.24	$-2.18	—	—	—
Book Value per Share (USD)	$41.78	$32.87	$27.58	$20.27	$23.55	$14.82	$6.52	$4.80	—
Tangible Book Value per Share (USD)	$41.78	$32.87	$27.58	$20.27	$23.55	$14.82	$6.52	$4.80	—
Basic Weighted Avg Shares (shares)	28.94M	28.59M	27.15M	25.49M	22.20M	18.79M	—	—	—

🏦 How resilient is the balance sheet? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2017 10-K ↗	FY 2017 Dec 31, 2016 10-K ↗
Working Capital (USD)	$921.66M	$640.05M	$554.82M	$354.93M	$416.53M	$259.61M	$192.55M	$49.27M	$2.13M
LT Debt (USD)	—	—	—	—	—	—	—	$4.25M	—
Total Equity (USD)	$1.22B	$946.38M	$778.64M	$522.23M	$593.58M	$292.08M	$113.23M	$49.47M	$289.00K

📋 What is driving earnings? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2017 10-K ↗	FY 2017 Dec 31, 2016 10-K ↗
Sales/Revenue/Turnover (USD)	$389.13M	$290.51M	$50.70M	$0.00	—	—	—	—	—
Depreciation Expense (USD)	$5.72M	$5.97M	$5.01M	$2.64M	$2.77M	$1.85M	$1.09M	$23.00K	$2.00K
Net Income, GAAP (USD)	$204.83M	$89.16M	$10.93M	$-139.97M	$-69.57M	$-32.17M	$-19.09M	$-7.92M	$-1.15M
Operating Cash Flow (USD)	$200.87M	$123.42M	$-88.80M	$-100.57M	$-47.94M	$-26.08M	$-18.69M	—	—

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bar_chart Data from SEC EDGAR XBRL filings

Synced 4 days ago 9 years · 38 quarters

Krystal Biotech, Inc.

Analytical Summary

9-Year Financial Trajectory

Bullish Indicators

Bearish Risks

Health Breakdown

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