Krystal Biotech, Inc.
KRYSAnalytical Summary
Krystal Biotech, Inc. shows strong fundamentals with top-quartile Return on Common Equity (%) and Profit Margin (%). The company's metrics support a bullish outlook for growth-oriented investors.
9-Year Financial Trajectory
AnnualBullish Indicators
- Operating Margin (%)Operating Margin (%) is in the top quartile
- Profit Margin (%)Profit Margin (%) is in the top quartile
- Return on Common Equity (%)Return on Common Equity (%) is in the top quartile
Bearish Risks
- No bearish risks detected.
Health Breakdown
Statement lens
Choose the reporting cadence, isolate a period range, or search directly for a metric.
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2017 10-K ↗ | FY 2017 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|
| Revenue Growth YoY (%) |
33.9%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+324%)
|
473.0%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+5813%)
|
— | — | — | — | — | — | — |
| EPS Growth YoY (%) |
126.9%
Excellent
↓
Excellent
Declining
Year-over-year change in earnings per share
Optimal:
> 10%
|
680.0%
Excellent
↑
Excellent
Improving
Year-over-year change in earnings per share
Optimal:
> 10%
|
N/M |
-75.4%
Weak
Weak
Year-over-year change in earnings per share
Optimal:
> 10%
|
-83.0%
Weak
Weak
Year-over-year change in earnings per share
Optimal:
> 10%
|
— | — | — | — |
| Net Income Growth YoY (%) |
129.7%
Excellent
↓
Excellent
Declining
Year-over-year change in net income |
715.6%
Excellent
↑
Excellent
Improving
Year-over-year change in net income |
N/M |
-101.2%
Weak
↑
Weak
Improving
Year-over-year change in net income |
-116.3%
Weak
↑
Weak
Improving
Year-over-year change in net income |
-68.5%
Weak
↑
Weak
Improving
Year-over-year change in net income |
-141.0%
Weak
Weak
Year-over-year change in net income |
-588.7%
Weak
Weak
Year-over-year change in net income |
— |
| FCF Growth YoY (%) |
56.6%
Excellent
↑
Excellent
Improving
Year-over-year change in free cash flow |
N/M |
38.5%
Excellent
↑
Excellent
Improving
Year-over-year change in free cash flow |
-15.0%
Weak
Weak
Year-over-year change in free cash flow |
-140.5%
Weak
Weak
Year-over-year change in free cash flow |
— | — | — | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2017 10-K ↗ | FY 2017 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|
| Operating Margin (%) (%) |
41.5%
Excellent
↑
Excellent
Improving
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Above avg (+176%)
|
22.6%
Good
Good
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Above avg (+51%)
|
-216.4%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1543%)
|
— | — | — | — | — | — |
| Effective Tax Rate (%) (%) |
-8.1%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
6.5%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
15.2%
Good
Good
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
0.0%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
— | — | — | — | — |
| Profit Margin (%) (%) |
52.6%
Excellent
↑
Excellent
Improving
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Above avg (+339%)
|
30.7%
Excellent
Excellent
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Above avg (+156%)
|
21.6%
Excellent
Excellent
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Above avg (+80%)
|
— | — | — | — | — | — |
| FCF Margin (%) (%) |
48.5%
Excellent
↑
Excellent
Improving
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
41.0%
Excellent
Excellent
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-198.4%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
— | — | — | — | — | — |
| FCF / Net Income (x) |
0.92x
Caution
↑
Caution
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.34x
Good
↑
Good
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
-9.20x
Weak
↓
Weak
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.10x
Fair
↓
Fair
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.67x
Excellent
↑
Excellent
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.27x
Good
Good
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.31x
Good
Good
Free cash flow relative to reported net income
Optimal:
> 1x
|
— | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2017 10-K ↗ | FY 2017 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|
| Return on Invested Capital (%) |
14.3%
Good
↑
Good
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
6.5%
Caution
↑
Caution
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-11.9%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-27.8%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-9.1%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-8.9%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-15.4%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-7.0%
Weak
Weak
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-312.4%
Weak
Weak
Return earned on debt + equity capital invested
Optimal:
> 10%
|
| Return on Capital (%) (%) |
12.1%
Good
↑
Good
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
6.2%
Caution
↑
Caution
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-13.4%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-26.0%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-10.9%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-10.6%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-10.6%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-9.5%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
-52.4%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
| Return on Common Equity (%) (%) |
16.8%
Good
↑
Good
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Above avg (+12%)
|
9.4%
Caution
↑
Caution
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-37%)
|
1.4%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-91%)
|
-26.8%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-279%)
|
-11.7%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-178%)
|
-11.0%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-173%)
|
-16.9%
Weak
Weak
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-212%)
|
-16.0%
Weak
Weak
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-207%)
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2017 10-K ↗ | FY 2017 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|
| Debt to Equity (x) | — | — | — | — | — | — | — |
0.09x
Excellent
Excellent
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-86%)
|
— |
| Interest Coverage (x) | — | — | — | — |
-45.76x
Weak
Weak
Operating income divided by interest expense
Optimal:
> 5x
|
— | — | — | — |
| Net Debt (USD) | $-496.30M | $-344.87M | $-358.33M | $-161.90M | $-341.25M | $-268.27M | $-187.51M | $-45.34M | $-1.92M |
| Debt / EBITDA (x) | — | — | — | — | — | — | — |
-0.90x
Excellent
Excellent
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2017 10-K ↗ | FY 2017 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|
| Working Capital (USD) | $921.66M | $640.05M | $554.82M | $354.93M | $416.53M | $259.61M | $192.55M | $49.27M | $2.13M |
| LT Debt (USD) | — | — | — | — | — | — | — | $4.25M | — |
| Total Equity (USD) | $1.22B | $946.38M | $778.64M | $522.23M | $593.58M | $292.08M | $113.23M | $49.47M | $289.00K |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2017 10-K ↗ | FY 2017 Dec 31, 2016 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue/Turnover (USD) | $389.13M | $290.51M | $50.70M | $0.00 | — | — | — | — | — |
| Depreciation Expense (USD) | $5.72M | $5.97M | $5.01M | $2.64M | $2.77M | $1.85M | $1.09M | $23.00K | $2.00K |
| Net Income, GAAP (USD) | $204.83M | $89.16M | $10.93M | $-139.97M | $-69.57M | $-32.17M | $-19.09M | $-7.92M | $-1.15M |
| Operating Cash Flow (USD) | $200.87M | $123.42M | $-88.80M | $-100.57M | $-47.94M | $-26.08M | $-18.69M | — | — |
Secondary lens
Benchmark Lens
Compare KRYS against peers after checking the statement evidence.
Open lens
Benchmark Lens
Compare KRYS against peers after checking the statement evidence.
Signals
Key bullish and bearish indicators for KRYS
Operating Margin (%) is in the top quartile
Profit Margin (%) is in the top quartile
Return on Common Equity (%) is in the top quartile
No bearish signals detected
Percentile Rankings
How KRYS compares to all companies
Peer Comparison
KRYS vs similar peers
Compare KRYS with peers
Stack KRYS against similar companies across every metric on this page.
north_east Open comparisonbar_chart Data from SEC EDGAR XBRL filings
Synced 1 week ago 9 years · 36 quarters