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Ultragenyx Pharmaceutical Inc.

RARE

$15.56 ▼ -1.60 (-9.32%) at close

15 Visible periods

28 Metrics

Peer-ranked Benchmarks

Price Chart

Health

Poor

Bearish

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Analytical Summary

Ultragenyx Pharmaceutical Inc. faces fundamental challenges with weakness in Profit Margin (%) and Operating Margin (%). The fundamentals warrant careful consideration of downside risks.

Market Cap $1.5B

Dividend Yield —

Revenue Growth 20.2% ↘

Op. Margin -79.5% ↗

ROIC 673.4% ↗

FCF / Share $-4.79 ↘

Trailing P/E —

Price / Book —

FCF Yield —

Debt / Equity —

info Valuation on last close. End-of-day price, Nov 5, 2026.

15-Year Financial Trajectory

Annual

Metric Value Trend Year over Year Percentile

Revenue Total top-line sales

$673.00M

↑ +20.2% —

Net Income Profit after all expenses

$-575.00M

↓ -1.1% —

Operating Margin Operating profit as % of sales

-79.5%

↑ +16.9% 3th

FCF / Share Free cash flow per share

$-4.79

↓ -2.9% —

trending_up

Bullish Indicators

No bullish signals detected.

warning

Bearish Risks

Operating Margin (%)Operating Margin (%) is in the bottom quartile
Profit Margin (%)Profit Margin (%) is in the bottom quartile

Health Breakdown

Profitability ↑

Cash Quality ↓

Dividend History

Dividend / share · sourced from SEC filings

$0.00 Latest / share

FY 2014

$0.00

FY 2015

FY 2016

FY 2017

FY 2018

FY 2019

FY 2020

FY 2021

FY 2022

FY 2023

FY 2024

FY 2025

Financial view

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📈 Is growth accelerating? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Revenue Growth YoY (%)	20.2% Excellent ↑ Excellent Improving Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+152%)	29.0% Excellent ↑ Excellent Improving Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+262%)	19.5% Good ↓ Good Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+144%)	3.4% Caution ↓ Caution Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-58%)	29.7% Excellent ↓ Excellent Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+271%)	161.3% Excellent ↓ Excellent Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+1917%)	101.4% Excellent ↓ Excellent Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+1168%)	1871.5% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+23293%)	1863.9% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+23199%)	—	—	—	—	—	—
EPS Growth YoY (%)	7.3% Fair ↑ Fair Improving Year-over-year change in earnings per share Optimal: > 10%	23.8% Good ↑ Good Improving Year-over-year change in earnings per share Optimal: > 10%	18.5% Good Good Year-over-year change in earnings per share Optimal: > 10%	-51.0% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	—	—	—	—	—	—	—	—	—	—	—
Net Income Growth YoY (%)	-1.1% Weak ↑ Weak Improving Year-over-year change in net income	6.2% Fair ↑ Fair Improving Year-over-year change in net income	14.2% Fair ↑ Fair Improving Year-over-year change in net income	-55.8% Weak ↑ Weak Improving Year-over-year change in net income	-143.4% Weak ↓ Weak Declining Year-over-year change in net income	53.7% Excellent ↑ Excellent Improving Year-over-year change in net income	-103.8% Weak ↓ Weak Declining Year-over-year change in net income	34.6% Excellent ↑ Excellent Improving Year-over-year change in net income	-22.9% Weak ↑ Weak Improving Year-over-year change in net income	-68.8% Weak ↑ Weak Improving Year-over-year change in net income	-143.5% Weak ↓ Weak Declining Year-over-year change in net income	-70.5% Weak Weak Year-over-year change in net income	-114.7% Weak Weak Year-over-year change in net income	—	—
FCF Growth YoY (%)	-2.9% Weak ↓ Weak Declining Year-over-year change in free cash flow	34.1% Excellent ↑ Excellent Improving Year-over-year change in free cash flow	0.6% Caution Caution Year-over-year change in free cash flow	-16.9% Weak Weak Year-over-year change in free cash flow	—	—	—	—	—	—	—	—	—	—	—
Revenue CAGR 3Y (%)	22.8% Excellent ↓ Excellent Declining Compound annual revenue growth over 3 years	16.8% Excellent ↓ Excellent Declining Compound annual revenue growth over 3 years	17.0% Excellent ↓ Excellent Declining Compound annual revenue growth over 3 years	51.9% Excellent ↓ Excellent Declining Compound annual revenue growth over 3 years	89.7% Excellent ↓ Excellent Declining Compound annual revenue growth over 3 years	369.9% Excellent Excellent Compound annual revenue growth over 3 years	820.4% Excellent Excellent Compound annual revenue growth over 3 years	—	—	—	—	—	—	—	—
Revenue CAGR 5Y (%)	19.9% Excellent ↓ Excellent Declining Compound annual revenue growth over 5 years	40.1% Excellent ↓ Excellent Declining Compound annual revenue growth over 5 years	53.2% Excellent ↓ Excellent Declining Compound annual revenue growth over 5 years	168.3% Excellent Excellent Compound annual revenue growth over 5 years	383.5% Excellent Excellent Compound annual revenue growth over 5 years	—	—	—	—	—	—	—	—	—	—

💰 Are margins durable? 5 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Operating Margin (%) (%)	-79.5% Weak ↑ Weak Improving Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-630%)	-95.7% Weak ↑ Weak Improving Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-738%)	-131.1% Weak → Weak Stable Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-974%)	-178.6% Weak ↑ Weak Improving Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1291%)	-108.6% Weak ↑ Weak Improving Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-824%)	-121.8% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-912%)	-409.0% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-2827%)	—	—	—	—	—	—	—	—
Effective Tax Rate (%) (%)	-0.7% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	-0.4% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.3% Excellent ↑ Excellent Improving Actual taxes paid relative to pre-tax income Optimal: 15-25%	-0.8% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	-0.2% Excellent ↑ Excellent Improving Actual taxes paid relative to pre-tax income Optimal: 15-25%	-0.7% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	-0.8% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	-0.3% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	5.1% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	-0.0% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	—	—	—	—	—
Profit Margin (%) (%)	-85.4% Weak ↑ Weak Improving Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-812%)	-101.6% Weak ↑ Weak Improving Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-947%)	-139.7% Weak ↓ Weak Declining Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1264%)	-194.7% Weak → Weak Stable Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1723%)	-129.2% Weak ↑ Weak Improving Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1177%)	-68.8% Weak ↑ Weak Improving Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-674%)	-388.3% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-3336%)	-383.7% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-3298%)	—	—	—	—	—	—	—
FCF Margin (%) (%)	-70.1% Weak ↑ Weak Improving Free cash flow as a percentage of revenue Optimal: > 10%	-75.2% Weak ↑ Weak Improving Free cash flow as a percentage of revenue Optimal: > 10%	-119.5% Weak ↓ Weak Declining Free cash flow as a percentage of revenue Optimal: > 10%	-136.7% Weak ↑ Weak Improving Free cash flow as a percentage of revenue Optimal: > 10%	-117.2% Weak ↑ Weak Improving Free cash flow as a percentage of revenue Optimal: > 10%	-65.0% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	-357.0% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	—	—	—	—	—	—	—	—
FCF / Net Income (x)	0.82x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.74x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.86x Caution → Caution Stable Free cash flow relative to reported net income Optimal: > 1x	0.70x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.91x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.94x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.92x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	1.49x Good Good Free cash flow relative to reported net income Optimal: > 1x	0.85x Caution Caution Free cash flow relative to reported net income Optimal: > 1x	—	—	—	—	—	—

🎯 Is capital allocation efficient? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Return on Invested Capital (%)	673.4% Excellent ↑ Excellent Improving Return earned on debt + equity capital invested Optimal: > 10%	-210.9% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-206.1% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-185.6% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-41.5% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-28.8% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-65.4% Weak → Weak Stable Return earned on debt + equity capital invested Optimal: > 10%	-61.1% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-81.4% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-52.3% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-22.0% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-24.3% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	34.1% Excellent Excellent Return earned on debt + equity capital invested Optimal: > 10%	46.7% Excellent Excellent Return earned on debt + equity capital invested Optimal: > 10%	—
Return on Capital (%) (%)	-34.9% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-35.7% Weak → Weak Stable Operating profit relative to total assets Optimal: > 10%	-38.2% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-42.0% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-25.1% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-18.8% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-37.4% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-51.6% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-67.0% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-45.9% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-26.4% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-28.7% Weak Weak Operating profit relative to total assets Optimal: > 10%	-54.1% Weak Weak Operating profit relative to total assets Optimal: > 10%	—	—
Return on Common Equity (%) (%)	—	-223.1% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1588%)	-220.3% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1568%)	-200.7% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1438%)	-49.2% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-428%)	-16.2% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-208%)	-61.6% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-511%)	-32.5% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-316%)	-78.8% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-625%)	-51.9% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-446%)	-27.4% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-283%)	-32.3% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-316%)	46.9% Excellent Excellent Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+212%)	60.4% Excellent Excellent Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+303%)	—

⚖️ Is the balance sheet risky? 1 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Net Debt (USD)	$-421.00M	$-174.00M	$-213.58M	$-132.94M	$-307.58M	$-713.53M	$-433.58M	$-113.43M	$-100.49M	$-161.12M	$-93.57M	$-24.32M	$-7.43M	$-86.19M	$-10.64M

📊 What does each share earn? 7 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Revenue per Share (USD)	$6.83	$6.19	$5.90	$5.20	$5.18	—	—	—	—	—	—	—	—	—	—
Basic EPS, GAAP (USD)	$-5.83	$-6.29	$-8.25	$-10.12	$-6.70	—	—	—	—	—	—	—	—	—	—
Free Cash Flow per Share (USD)	$-4.79	$-4.65	$-7.06	$-7.10	$-6.07	—	—	—	—	—	—	—	—	—	—
Dividend per Share (USD)	—	—	—	—	—	—	—	—	—	—	$0.00	—	—	—	—
Book Value per Share (USD)	$-0.83	$2.76	$3.35	$5.02	$13.30	$17.28	$11.30	$11.97	$8.68	$11.49	$13.66	$5.79	$-19.87	$-8.67	—
Tangible Book Value per Share (USD)	$-3.11	$0.36	$0.79	$2.11	$10.78	$14.65	$8.31	$8.56	$4.47	$11.49	$13.66	$5.79	$-19.87	$-8.67	—
Basic Weighted Avg Shares (shares)	98.60M	90.50M	73.54M	69.91M	67.80M	—	—	—	—	—	36.78M	28.76M	3.58M	3.12M	—

🏦 How resilient is the balance sheet? 2 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Working Capital (USD)	$567.00M	$473.00M	$451.75M	$622.69M	$675.24M	$1.11B	$747.72M	$447.64M	$198.57M	$341.44M	$422.29M	$180.90M	$49.30M	—	—
Total Equity (USD)	$-80.00M	$255.00M	$275.41M	$352.49M	$922.56M	$1.15B	$653.76M	$608.91M	$383.45M	$473.97M	$531.09M	$184.94M	$-74.82M	$-27.05M	$-7.96M

📋 What is driving earnings? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Sales/Revenue/Turnover (USD)	$673.00M	$560.00M	$434.25M	$363.33M	$351.41M	$271.03M	$103.71M	$51.49M	$2.61M	$133.00K	—	—	—	—	—
Depreciation Expense (USD)	$35.00M	$36.00M	$26.01M	$18.22M	$13.24M	$12.26M	$8.54M	$19.54M	$5.83M	$3.42M	$1.38M	$684.00K	$444.00K	$313.00K	—
Net Income, GAAP (USD)	$-575.00M	$-569.00M	$-606.64M	$-707.42M	$-454.02M	$-186.57M	$-402.73M	$-197.61M	$-302.14M	$-245.87M	$-145.62M	$-59.80M	$-35.07M	$-16.33M	—
Operating Cash Flow (USD)	$-466.00M	$-414.00M	$-474.81M	$-380.46M	$-338.69M	$-132.22M	$-345.38M	$-290.57M	$-253.84M	—	—	—	—	—	—

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bar_chart Data from SEC EDGAR XBRL filings

Synced 5 days ago 15 years · 56 quarters

Ultragenyx Pharmaceutical Inc.

Analytical Summary

15-Year Financial Trajectory

Bullish Indicators

Bearish Risks

Health Breakdown

Dividend History

Statement lens

Benchmark Lens

Signals

Percentile Rankings

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