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SERA PROGNOSTICS, INC.

SERA

$2.06 ▲ +0.09 (+4.56%) at close

7 Visible periods

25 Metrics

Peer-ranked Benchmarks

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Health

Poor

Bearish

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Analytical Summary

SERA PROGNOSTICS, INC. faces fundamental challenges with weakness in Return on Common Equity (%). The fundamentals warrant careful consideration of downside risks.

Market Cap $98.2M

Dividend Yield —

Revenue Growth 5.2% ↗

Op. Margin —

ROIC -48.4% ↗

FCF / Share $-0.55 ↘

Trailing P/E —

Price / Book 1.3x

FCF Yield —

Debt / Equity —

info Valuation on last close. End-of-day price, Aug 7, 2026.

7-Year Financial Trajectory

Annual

Metric Value Trend Year over Year Percentile

Revenue Total top-line sales

$81.00K

↑ +5.2% —

Net Income Profit after all expenses

$-31.93M

↑ +2.9% —

FCF / Share Free cash flow per share

$-0.55

↓ -28.7% —

trending_up

Bullish Indicators

No bullish signals detected.

warning

Bearish Risks

Return on Common Equity (%)Return on Common Equity (%) is in the bottom quartile

Health Breakdown

Returns ↓

Financial Health ↓

Cash Quality ↓

Financial view

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📈 Is growth accelerating? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗
Revenue Growth YoY (%)	5.2% Fair ↓ Fair Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-35%)	-74.8% Weak ↓ Weak Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-1035%)	14.2% Good ↓ Good Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+77%)	226.8% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+2735%)	228.0% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+2750%)	—	—
EPS Growth YoY (%)	32.3% Excellent ↑ Excellent Improving Year-over-year change in earnings per share Optimal: > 10%	14.7% Fair ↓ Fair Declining Year-over-year change in earnings per share Optimal: > 10%	18.9% Good ↓ Good Declining Year-over-year change in earnings per share Optimal: > 10%	38.6% Excellent Excellent Year-over-year change in earnings per share Optimal: > 10%	81.7% Excellent Excellent Year-over-year change in earnings per share Optimal: > 10%	—	—
Net Income Growth YoY (%)	2.9% Caution ↑ Caution Improving Year-over-year change in net income	9.2% Fair ↑ Fair Improving Year-over-year change in net income	18.0% Good ↑ Good Improving Year-over-year change in net income	-26.2% Weak Weak Year-over-year change in net income	-76.4% Weak Weak Year-over-year change in net income	—	—
FCF Growth YoY (%)	-28.7% Weak ↓ Weak Declining Year-over-year change in free cash flow	50.9% Excellent → Excellent Stable Year-over-year change in free cash flow	23.5% Good ↓ Good Declining Year-over-year change in free cash flow	47.9% Excellent Excellent Year-over-year change in free cash flow	79.9% Excellent Excellent Year-over-year change in free cash flow	—	—
Revenue CAGR 3Y (%)	-32.9% Weak ↓ Weak Declining Compound annual revenue growth over 3 years	-2.1% Weak Weak Compound annual revenue growth over 3 years	130.5% Excellent Excellent Compound annual revenue growth over 3 years	—	—	—	—
Revenue CAGR 5Y (%)	26.5% Excellent Excellent Compound annual revenue growth over 5 years	—	—	—	—	—	—

💰 Are margins durable? 2 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗
Effective Tax Rate (%) (%)	0.0% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.0% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	—	—	—	—	—
FCF / Net Income (x)	0.83x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.43x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	0.75x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.80x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.94x Caution Caution Free cash flow relative to reported net income Optimal: > 1x	0.86x Caution Caution Free cash flow relative to reported net income Optimal: > 1x	—

🎯 Is capital allocation efficient? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗
Return on Invested Capital (%)	-48.4% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-76.6% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-44.8% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-36.5% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-20.2% Weak Weak Return earned on debt + equity capital invested Optimal: > 10%	11.3% Good Good Return earned on debt + equity capital invested Optimal: > 10%	—
Return on Capital (%) (%)	-35.8% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-50.5% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-41.7% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-39.2% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-24.1% Weak Weak Operating profit relative to total assets Optimal: > 10%	-121.5% Weak Weak Operating profit relative to total assets Optimal: > 10%	—
Return on Common Equity (%) (%)	-42.3% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-382%)	-68.8% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-559%)	-51.7% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-444%)	-44.7% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-398%)	-25.3% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-268%)	15.8% Good Good Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+5%)	—

⚖️ Is the balance sheet risky? 2 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗
Interest Coverage (x)	-4056.00x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-1308.39x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-724.02x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-951.08x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-29.79x Weak Weak Operating income divided by interest expense Optimal: > 5x	-71.88x Weak Weak Operating income divided by interest expense Optimal: > 5x	—
Net Debt (USD)	$-3.94M	$-4.04M	$-3.88M	$-29.88M	$-58.93M	$-13.53M	—

📊 What does each share earn? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗
Revenue per Share (USD)	$0.00	$0.00	$0.01	$0.01	$0.01	$0.02	—
Basic EPS, GAAP (USD)	$-0.67	$-0.99	$-1.16	$-1.43	$-2.33	$-12.76	—
Free Cash Flow per Share (USD)	$-0.55	$-0.43	$-0.88	$-1.14	$-2.20	$-10.94	—
Book Value per Share (USD)	$1.58	$1.44	$2.25	$3.20	$9.24	$-80.71	—
Tangible Book Value per Share (USD)	$1.56	$1.41	$2.25	$3.20	$9.24	$-80.71	—
Basic Weighted Avg Shares (shares)	47.66M	33.16M	31.20M	30.94M	15.00M	1.56M	—

🏦 How resilient is the balance sheet? 2 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗
Working Capital (USD)	$16.58M	$22.83M	$36.90M	$74.59M	$101.84M	$2.49M	—
Total Equity (USD)	$75.41M	$47.80M	$70.16M	$98.94M	$138.56M	$-125.57M	$-106.62M

📋 What is driving earnings? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗
Sales/Revenue/Turnover (USD)	$81.00K	$77.00K	$306.00K	$268.00K	$82.00K	$25.00K	—
Depreciation Expense (USD)	$940.00K	$833.00K	$900.00K	$756.00K	$659.00K	$895.00K	—
Net Income, GAAP (USD)	$-31.93M	$-32.90M	$-36.24M	$-44.19M	$-35.01M	$-19.85M	—
Operating Cash Flow (USD)	$-25.62M	$-14.19M	$-27.19M	$-34.61M	$-31.64M	$-16.87M	—

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bar_chart Data from SEC EDGAR XBRL filings

Synced 1 week ago 7 years · 26 quarters

SERA PROGNOSTICS, INC.

Analytical Summary

7-Year Financial Trajectory

Bullish Indicators

Bearish Risks

Health Breakdown

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