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SUTRO BIOPHARMA, INC.

STRO

$9.16 ▼ -0.81 (-8.07%) at close

11 Visible periods

31 Metrics

Peer-ranked Benchmarks

Price Chart

Health

Fair

Moderately Bearish

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Analytical Summary

SUTRO BIOPHARMA, INC. faces fundamental challenges with weakness in Profit Margin (%) and Operating Margin (%). On the positive side, Return on Common Equity (%) remains strong. Investors should exercise caution and monitor for improvement in key metrics.

Market Cap $77.8M

Dividend Yield —

Revenue Growth 65.2% ↗

Op. Margin -154.5% ↗

ROIC 119.5% ↗

FCF / Share $-20.86 ↗

Trailing P/E —

Price / Book —

FCF Yield —

Debt / Equity —

info Valuation on last close. End-of-day price, Nov 5, 2026.

11-Year Financial Trajectory

Annual

Metric Value Trend Year over Year Percentile

Revenue Total top-line sales

$102.48M

↑ +65.2% —

Net Income Profit after all expenses

$-191.09M

↑ +16.0% —

Operating Margin Operating profit as % of sales

-154.5%

↑ +59.8% 1th

FCF / Share Free cash flow per share

$-20.86

↑ +15.8% —

Long-Term Debt Long-term obligations

$4.06M

↓ -75.0% —

trending_up

Bullish Indicators

Return on Common Equity (%)Return on Common Equity (%) is in the top quartile

warning

Bearish Risks

Operating Margin (%)Operating Margin (%) is in the bottom quartile
Profit Margin (%)Profit Margin (%) is in the bottom quartile

Health Breakdown

Profitability ↓

Returns

100

Cash Quality ↑

Financial view

Statement lens

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📈 Is growth accelerating? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗
Revenue Growth YoY (%)	65.2% Excellent ↑ Excellent Improving Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+715%)	-59.6% Weak ↓ Weak Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-846%)	126.8% Excellent ↑ Excellent Improving Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+1485%)	9.5% Fair ↓ Fair Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+19%)	44.8% Excellent ↑ Excellent Improving Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+461%)	-0.0% Weak ↑ Weak Improving Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-100%)	11.2% Good ↑ Good Improving Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+40%)	-25.7% Weak Weak Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-422%)	-13.4% Weak Weak Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-267%)	—	—
EPS Growth YoY (%)	23.5% Good ↑ Good Improving Year-over-year change in earnings per share Optimal: > 10%	-65.2% Weak ↓ Weak Declining Year-over-year change in earnings per share Optimal: > 10%	24.3% Good Good Year-over-year change in earnings per share Optimal: > 10%	-2.6% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	—	—	—	—	—	—	—
Net Income Growth YoY (%)	16.0% Good ↑ Good Improving Year-over-year change in net income	-113.0% Weak ↓ Weak Declining Year-over-year change in net income	10.4% Fair ↑ Fair Improving Year-over-year change in net income	-12.9% Weak ↑ Weak Improving Year-over-year change in net income	-228.5% Weak ↓ Weak Declining Year-over-year change in net income	42.4% Excellent ↑ Excellent Improving Year-over-year change in net income	-57.8% Weak Weak Year-over-year change in net income	-79.4% Weak Weak Year-over-year change in net income	N/M	—	—
FCF Growth YoY (%)	15.8% Good Good Year-over-year change in free cash flow	-33.4% Weak Weak Year-over-year change in free cash flow	N/M	N/M	—	—	—	—	—	—	—
Revenue CAGR 3Y (%)	14.8% Good ↓ Good Declining Compound annual revenue growth over 3 years	0.1% Weak ↓ Weak Declining Compound annual revenue growth over 3 years	53.2% Excellent ↑ Excellent Improving Compound annual revenue growth over 3 years	16.6% Excellent ↑ Excellent Improving Compound annual revenue growth over 3 years	17.2% Excellent ↑ Excellent Improving Compound annual revenue growth over 3 years	-6.2% Weak Weak Compound annual revenue growth over 3 years	-10.6% Weak Weak Compound annual revenue growth over 3 years	—	—	—	—
Revenue CAGR 5Y (%)	19.1% Excellent ↑ Excellent Improving Compound annual revenue growth over 5 years	7.7% Fair ↓ Fair Declining Compound annual revenue growth over 5 years	32.0% Excellent ↑ Excellent Improving Compound annual revenue growth over 5 years	5.5% Fair Fair Compound annual revenue growth over 5 years	0.7% Weak Weak Compound annual revenue growth over 5 years	—	—	—	—	—	—

💰 Are margins durable? 5 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗
Operating Margin (%) (%)	-154.5% Weak ↑ Weak Improving Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1130%)	-384.3% Weak ↓ Weak Declining Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-2662%)	-58.1% Weak ↑ Weak Improving Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-487%)	-190.3% Weak ↓ Weak Declining Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1368%)	-159.2% Weak ↓ Weak Declining Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1161%)	-166.3% Weak ↓ Weak Declining Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1209%)	-129.8% Weak ↓ Weak Declining Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-965%)	-96.9% Weak ↓ Weak Declining Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-746%)	-37.2% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-348%)	2.3% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-85%)	—
Effective Tax Rate (%) (%)	0.0% Excellent ↑ Excellent Improving Actual taxes paid relative to pre-tax income Optimal: 15-25%	-1.0% Excellent ↑ Excellent Improving Actual taxes paid relative to pre-tax income Optimal: 15-25%	-20.5% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	-2.1% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	—	—	—	—	—	—	—
Profit Margin (%) (%)	-186.5% Weak ↑ Weak Improving Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1654%)	-366.6% Weak ↓ Weak Declining Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-3155%)	-69.5% Weak ↑ Weak Improving Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-679%)	-175.9% Weak ↓ Weak Declining Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1566%)	-170.6% Weak ↓ Weak Declining Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1521%)	-75.2% Weak ↑ Weak Improving Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-727%)	-130.4% Weak ↓ Weak Declining Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-1187%)	-91.9% Weak ↓ Weak Declining Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-866%)	-38.1% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-417%)	2.8% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-76%)	—
FCF Margin (%) (%)	-172.9% Weak ↓ Weak Declining Free cash flow as a percentage of revenue Optimal: > 10%	-308.7% Weak ↓ Weak Declining Free cash flow as a percentage of revenue Optimal: > 10%	-72.6% Weak ↑ Weak Improving Free cash flow as a percentage of revenue Optimal: > 10%	5.2% Caution ↑ Caution Improving Free cash flow as a percentage of revenue Optimal: > 10%	-132.0% Weak ↓ Weak Declining Free cash flow as a percentage of revenue Optimal: > 10%	-158.7% Weak ↓ Weak Declining Free cash flow as a percentage of revenue Optimal: > 10%	-152.2% Weak ↓ Weak Declining Free cash flow as a percentage of revenue Optimal: > 10%	29.0% Excellent ↑ Excellent Improving Free cash flow as a percentage of revenue Optimal: > 10%	-78.1% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	-29.4% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	—
FCF / Net Income (x)	0.93x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.84x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	1.05x Fair ↑ Fair Improving Free cash flow relative to reported net income Optimal: > 1x	-0.03x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	0.77x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	2.11x Excellent ↑ Excellent Improving Free cash flow relative to reported net income Optimal: > 1x	1.17x Fair ↑ Fair Improving Free cash flow relative to reported net income Optimal: > 1x	-0.32x Weak ↑ Weak Improving Free cash flow relative to reported net income Optimal: > 1x	2.05x Excellent Excellent Free cash flow relative to reported net income Optimal: > 1x	-10.31x Weak Weak Free cash flow relative to reported net income Optimal: > 1x	—

🎯 Is capital allocation efficient? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗
Return on Invested Capital (%)	119.5% Excellent ↑ Excellent Improving Return earned on debt + equity capital invested Optimal: > 10%	-540.2% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-70.0% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-56.4% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-28.0% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-15.7% Weak → Weak Stable Return earned on debt + equity capital invested Optimal: > 10%	-41.1% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-20.1% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	14.0% Good Good Return earned on debt + equity capital invested Optimal: > 10%	-1.2% Weak Weak Return earned on debt + equity capital invested Optimal: > 10%	—
Return on Capital (%) (%)	-91.1% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-61.6% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-19.0% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-31.7% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-28.9% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-18.0% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-35.5% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-16.7% Weak Weak Operating profit relative to total assets Optimal: > 10%	-47.3% Weak Weak Operating profit relative to total assets Optimal: > 10%	—	—
Return on Common Equity (%) (%)	144.3% Excellent ↑ Excellent Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+862%)	—	-71.4% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-576%)	-54.9% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-466%)	-41.8% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-379%)	-9.7% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-165%)	-57.0% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-480%)	-26.8% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-279%)	18.1% Good Good Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+20%)	-1.9% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-112%)	—

⚖️ Is the balance sheet risky? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗
Debt to Equity (x)	—	—	0.03x Excellent ↓ Excellent Declining Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-95%)	0.07x Excellent ↓ Excellent Declining Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-88%)	0.10x Excellent ↑ Excellent Improving Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-83%)	0.07x Excellent ↓ Excellent Declining Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-88%)	0.09x Excellent Excellent Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-85%)	0.11x Excellent Excellent Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-81%)	—	—	—
Interest Coverage (x)	—	-769.20x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-68.68x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-53.73x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-37.89x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-30.89x Weak ↑ Weak Improving Operating income divided by interest expense Optimal: > 5x	-50.43x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-22.93x Weak Weak Operating income divided by interest expense Optimal: > 5x	-31.49x Weak Weak Operating income divided by interest expense Optimal: > 5x	—	—
Net Debt (USD)	$-58.13M	$-190.30M	$-65.21M	$-30.98M	$-5.30M	$-181.61M	$3.92M	$-110.57M	$-22.02M	$-11.59M	—
Debt / EBITDA (x)	—	—	-0.05x Excellent ↑ Excellent Improving Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	-0.13x Excellent ↑ Excellent Improving Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	-0.27x Excellent ↑ Excellent Improving Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	-0.37x Excellent ↓ Excellent Declining Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	-0.18x Excellent Excellent Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	-0.45x Excellent Excellent Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	—	—	—

📊 What does each share earn? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗
Revenue per Share (USD)	$12.06	$8.02	$25.55	$13.36	$13.42	—	—	—	—	—	—
Basic EPS, GAAP (USD)	$-22.49	$-29.40	$-17.80	$-23.50	$-22.90	—	—	—	—	—	—
Free Cash Flow per Share (USD)	$-20.86	$-24.76	$-18.55	$0.70	$-17.71	—	—	—	—	—	—
Book Value per Share (USD)	$-15.43	$5.37	$24.53	$37.75	$54.52	$72.58	$42.33	$57.57	$-2.34K	—	—
Tangible Book Value per Share (USD)	$-15.43	$5.37	$24.53	$37.75	$54.52	$72.58	$42.33	$57.57	$-2.34K	—	—
Basic Weighted Avg Shares (shares)	8.50M	7.74M	6.02M	5.07M	4.61M	—	—	—	—	—	—

🏦 How resilient is the balance sheet? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗
Working Capital (USD)	$75.79M	$211.42M	$327.80M	$286.61M	$176.78M	$348.58M	$95.60M	$173.52M	$-6.33M	—	—
LT Debt (USD)	—	—	$4.06M	$16.27M	$25.11M	$24.55M	$8.88M	$14.72M	—	—	—
Total Equity (USD)	$-132.45M	$44.60M	$149.65M	$217.05M	$252.56M	$332.05M	$97.79M	$131.54M	$-109.00M	$-90.90M	$-93.90M

📋 What is driving earnings? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗
Sales/Revenue/Turnover (USD)	$102.48M	$62.04M	$153.73M	$67.77M	$61.88M	$42.72M	$42.74M	$38.42M	$51.74M	$59.73M	—
Depreciation Expense (USD)	$7.32M	$7.22M	$6.82M	$5.69M	$4.84M	$4.30M	$4.78M	$4.54M	$4.99M	$5.66M	—
Net Income, GAAP (USD)	$-191.09M	$-227.46M	$-106.79M	$-119.20M	$-105.54M	$-32.13M	$-55.74M	$-35.32M	$-19.69M	$1.70M	—
Operating Cash Flow (USD)	$-177.23M	$-191.54M	$-111.62M	$3.55M	$-81.68M	$-67.80M	$-65.02M	$12.68M	$-37.07M	$-13.15M	—

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bar_chart Data from SEC EDGAR XBRL filings

Synced 4 days ago 11 years · 38 quarters

SUTRO BIOPHARMA, INC.

Analytical Summary

11-Year Financial Trajectory

Bullish Indicators

Bearish Risks

Health Breakdown

Statement lens

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