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Wave Life Sciences Ltd.

WVE

$3.21 ▼ -0.40 (-10.94%) at close

14 Visible periods

28 Metrics

Peer-ranked Benchmarks

Price Chart

Health

Poor

Bearish

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Analytical Summary

Wave Life Sciences Ltd. faces fundamental challenges with weakness in Return on Common Equity (%). The fundamentals warrant careful consideration of downside risks.

Market Cap $541.4M

Dividend Yield —

Revenue Growth -60.5% ↘

Op. Margin None

ROIC -41.6% ↗

FCF / Share $-1.12 →

Trailing P/E —

Price / Book 1.2x

FCF Yield —

Debt / Equity —

info Valuation on last close. End-of-day price, Nov 5, 2026.

14-Year Financial Trajectory

Annual

Metric Value Trend Year over Year Percentile

Revenue Total top-line sales

$42.73M

↓ -60.5% —

Net Income Profit after all expenses

$-204.38M

↓ -110.7% —

Operating Margin Operating profit as % of sales

-101.9%

↓ -69.9% —

FCF / Share Free cash flow per share

$-1.12

↓ -1.5% —

trending_up

Bullish Indicators

No bullish signals detected.

warning

Bearish Risks

Profit Margin (%)Profit Margin (%) is in the bottom quartile
Return on Common Equity (%)Return on Common Equity (%) is in the bottom quartile

Health Breakdown

Profitability ↓

Returns ↑

Cash Quality ↑

Financial view

Statement lens

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📈 Is growth accelerating? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Revenue Growth YoY (%)	-60.5% Weak ↓ Weak Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-857%)	-4.4% Weak ↓ Weak Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-155%)	3005.1% Excellent ↑ Excellent Improving Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+37464%)	-91.1% Weak ↓ Weak Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-1239%)	104.0% Excellent → Excellent Stable Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+1200%)	25.6% Excellent ↓ Excellent Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+220%)	10.9% Good ↓ Good Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+36%)	270.3% Excellent ↓ Excellent Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+3278%)	162.2% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+1927%)	877.0% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+10862%)	—	—	—	—
EPS Growth YoY (%)	-72.9% Weak ↓ Weak Declining Year-over-year change in earnings per share Optimal: > 10%	-29.6% Weak ↓ Weak Declining Year-over-year change in earnings per share Optimal: > 10%	73.7% Excellent Excellent Year-over-year change in earnings per share Optimal: > 10%	13.1% Fair Fair Year-over-year change in earnings per share Optimal: > 10%	—	—	—	—	—	—	—	—	—	—
Net Income Growth YoY (%)	-110.7% Weak ↓ Weak Declining Year-over-year change in net income	-68.7% Weak ↓ Weak Declining Year-over-year change in net income	64.5% Excellent ↑ Excellent Improving Year-over-year change in net income	-32.4% Weak ↓ Weak Declining Year-over-year change in net income	18.5% Good ↑ Good Improving Year-over-year change in net income	22.6% Good ↑ Good Improving Year-over-year change in net income	-32.0% Weak ↑ Weak Improving Year-over-year change in net income	-43.8% Weak ↑ Weak Improving Year-over-year change in net income	-84.1% Weak ↑ Weak Improving Year-over-year change in net income	-188.5% Weak ↓ Weak Declining Year-over-year change in net income	-267.2% Weak Weak Year-over-year change in net income	-57.6% Weak Weak Year-over-year change in net income	—	—
FCF Growth YoY (%)	-1.5% Weak ↑ Weak Improving Year-over-year change in free cash flow	-467.5% Weak ↓ Weak Declining Year-over-year change in free cash flow	88.2% Excellent Excellent Year-over-year change in free cash flow	5.2% Fair Fair Year-over-year change in free cash flow	—	—	—	—	—	—	—	—	—	—
Revenue CAGR 3Y (%)	127.1% Excellent ↑ Excellent Improving Compound annual revenue growth over 3 years	38.3% Excellent ↑ Excellent Improving Compound annual revenue growth over 3 years	78.0% Excellent ↑ Excellent Improving Compound annual revenue growth over 3 years	-38.9% Weak ↓ Weak Declining Compound annual revenue growth over 3 years	41.6% Excellent ↓ Excellent Declining Compound annual revenue growth over 3 years	72.8% Excellent ↓ Excellent Declining Compound annual revenue growth over 3 years	120.8% Excellent Excellent Compound annual revenue growth over 3 years	356.0% Excellent Excellent Compound annual revenue growth over 3 years	—	—	—	—	—	—
Revenue CAGR 5Y (%)	16.3% Excellent ↓ Excellent Declining Compound annual revenue growth over 5 years	46.6% Excellent → Excellent Stable Compound annual revenue growth over 5 years	51.0% Excellent ↓ Excellent Declining Compound annual revenue growth over 5 years	-1.3% Weak ↓ Weak Declining Compound annual revenue growth over 5 years	94.1% Excellent Excellent Compound annual revenue growth over 5 years	165.6% Excellent Excellent Compound annual revenue growth over 5 years	—	—	—	—	—	—	—	—

💰 Are margins durable? 5 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Operating Margin (%) (%)	—	-101.9% Weak ↑ Weak Improving Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-780%)	-60.0% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-500%)	—	-310.1% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-2167%)	—	—	—	—	—	—	—	—	—
Effective Tax Rate (%) (%)	0.0% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.0% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	1.2% Excellent ↑ Excellent Improving Actual taxes paid relative to pre-tax income Optimal: 15-25%	-0.4% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.2% Excellent → Excellent Stable Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.6% Excellent ↑ Excellent Improving Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.0% Excellent ↑ Excellent Improving Actual taxes paid relative to pre-tax income Optimal: 15-25%	-0.0% Excellent ↑ Excellent Improving Actual taxes paid relative to pre-tax income Optimal: 15-25%	-0.8% Excellent ↑ Excellent Improving Actual taxes paid relative to pre-tax income Optimal: 15-25%	-1.1% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	-0.2% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	-1.6% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	9.0% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	—
Profit Margin (%) (%)	-478.3% Weak ↓ Weak Declining Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-4086%)	-89.6% Weak ↑ Weak Improving Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-846%)	-50.8% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-523%)	—	-298.4% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-2587%)	—	—	—	—	—	—	—	—	—
FCF Margin (%) (%)	-440.5% Weak ↓ Weak Declining Free cash flow as a percentage of revenue Optimal: > 10%	-140.3% Weak ↓ Weak Declining Free cash flow as a percentage of revenue Optimal: > 10%	-18.1% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	—	-218.6% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	—	—	-227.6% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	—	—	—	—	—	—
FCF / Net Income (x)	0.92x Caution → Caution Stable Free cash flow relative to reported net income Optimal: > 1x	1.57x Excellent ↑ Excellent Improving Free cash flow relative to reported net income Optimal: > 1x	0.36x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	0.80x Caution → Caution Stable Free cash flow relative to reported net income Optimal: > 1x	0.73x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.78x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.99x Caution ↑ Caution Improving Free cash flow relative to reported net income Optimal: > 1x	0.22x Weak Weak Free cash flow relative to reported net income Optimal: > 1x	1.01x Fair Fair Free cash flow relative to reported net income Optimal: > 1x	—	—	—	—	—

🎯 Is capital allocation efficient? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Return on Invested Capital (%)	-41.6% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-52.7% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-169.6% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	362.4% Excellent ↑ Excellent Improving Return earned on debt + equity capital invested Optimal: > 10%	-390.2% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-184.3% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-326.9% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-217.6% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-74.0% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-41.5% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-12.6% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-270.5% Weak Weak Return earned on debt + equity capital invested Optimal: > 10%	41.9% Excellent Excellent Return earned on debt + equity capital invested Optimal: > 10%	—
Return on Capital (%) (%)	-33.7% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-31.3% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-24.7% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-111.2% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-61.4% Weak → Weak Stable Operating profit relative to total assets Optimal: > 10%	-54.9% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-73.3% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-53.9% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-56.3% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-33.6% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-11.7% Weak Weak Operating profit relative to total assets Optimal: > 10%	-183.6% Weak Weak Operating profit relative to total assets Optimal: > 10%	—	—
Return on Common Equity (%) (%)	-39.4% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-363%)	-46.3% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-409%)	-145.1% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1067%)	—	—	-181.1% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1307%)	—	-199.9% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1433%)	-73.0% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-587%)	-41.1% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-374%)	-12.5% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-183%)	-258.0% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-1820%)	42.7% Excellent Excellent Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+185%)	—

⚖️ Is the balance sheet risky? 2 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Interest Coverage (x)	—	—	—	—	—	—	—	—	—	-1907.83x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	—	-62.72x Weak Weak Operating income divided by interest expense Optimal: > 5x	-39.71x Weak Weak Operating income divided by interest expense Optimal: > 5x	—
Net Debt (USD)	$-602.07M	$-302.08M	$-200.35M	$-88.50M	$-150.56M	$-184.50M	$-147.16M	$-174.82M	$-142.50M	$-150.29M	$-161.22M	$-1.05M	$-439.00K	$-379.00K

📊 What does each share earn? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Revenue per Share (USD)	$0.25	$0.78	$1.07	$0.05	$0.79	—	—	—	—	—	—	—	—	—
Basic EPS, GAAP (USD)	$-1.21	$-0.70	$-0.54	$-2.05	$-2.36	—	—	—	—	—	—	—	—	—
Free Cash Flow per Share (USD)	$-1.12	$-1.10	$-0.19	$-1.64	$-1.73	—	—	—	—	—	—	—	—	—
Book Value per Share (USD)	$2.76	$1.37	$0.33	$-0.52	$0.54	$1.70	$1.86	$2.49	$5.02	$5.74	$7.12	$0.48	—	—
Tangible Book Value per Share (USD)	$2.76	$1.37	$0.33	$-0.52	$0.54	$1.70	$1.86	$2.49	$5.02	$5.74	$7.12	$0.48	—	—
Basic Weighted Avg Shares (shares)	168.65M	138.28M	106.10M	78.86M	51.83M	—	—	—	—	—	—	—	—	—

🏦 How resilient is the balance sheet? 2 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Working Capital (USD)	$519.75M	$209.44M	$48.93M	$27.02M	$98.36M	$109.00M	$67.32M	$72.23M	$132.30M	$139.84M	$157.57M	$605.00K	—	—
Total Equity (USD)	$518.36M	$209.51M	$39.63M	$-45.09M	$32.50M	$82.78M	$63.73M	$73.35M	$139.61M	$134.86M	$153.49M	$2.03M	$-7.76M	$-4.58M

📋 What is driving earnings? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗
Sales/Revenue/Turnover (USD)	$42.73M	$108.30M	$113.31M	$3.65M	$40.96M	$20.08M	$15.98M	$14.41M	$3.89M	$1.49M	$152.00K	—	—	—
Depreciation Expense (USD)	$3.44M	$3.90M	$5.00M	$6.57M	$7.48M	$8.11M	$7.59M	$5.58M	$2.15M	—	—	—	—	—
Net Income, GAAP (USD)	$-204.38M	$-97.01M	$-57.51M	$-161.82M	$-122.25M	$-149.91M	$-193.64M	$-146.65M	$-101.98M	$-55.40M	$-19.20M	$-5.23M	$-3.32M	—
Operating Cash Flow (USD)	$-187.49M	$-151.03M	$-19.43M	$-127.78M	$-88.99M	$-115.98M	$-188.23M	$-22.86M	$-83.67M	—	—	—	—	—

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bar_chart Data from SEC EDGAR XBRL filings

Synced 4 days ago 14 years · 52 quarters

Wave Life Sciences Ltd.

Analytical Summary

14-Year Financial Trajectory

Bullish Indicators

Bearish Risks

Health Breakdown

Statement lens

Benchmark Lens

Signals

Percentile Rankings

Peer Comparison

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