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Xenon Pharmaceuticals Inc.

XENE

$63.44 ▼ -1.08 (-1.67%) at close

15 Visible periods

31 Metrics

Peer-ranked Benchmarks

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Health

Poor

Bearish

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Analytical Summary

Xenon Pharmaceuticals Inc. faces fundamental challenges with weakness in Return on Common Equity (%). The fundamentals warrant careful consideration of downside risks.

Market Cap $5.0B

Dividend Yield —

Revenue Growth None

Op. Margin None

ROIC -64.3% ↘

FCF / Share $-3.53 ↘

Trailing P/E —

Price / Book 8.7x

FCF Yield —

Debt / Equity —

info Valuation on last close. End-of-day price, Aug 7, 2026.

15-Year Financial Trajectory

Annual

Metric Value Trend Year over Year Percentile

Revenue Total top-line sales

$7.50M

— —

Net Income Profit after all expenses

$-345.91M

↓ -47.6% —

Operating Margin Operating profit as % of sales

-428.4%

↓ -340.3% —

FCF / Share Free cash flow per share

$-3.53

↓ -49.1% —

Long-Term Debt Long-term obligations

$10.89M

↓ -27.5% —

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Bullish Indicators

No bullish signals detected.

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Bearish Risks

Return on Common Equity (%)Return on Common Equity (%) is in the bottom quartile

Health Breakdown

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📈 Is growth accelerating? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Revenue Growth YoY (%)	—	—	—	-48.8% Weak ↓ Weak Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-710%)	-42.7% Weak Weak Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-634%)	371.0% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+4538%)	—	—	-82.8% Weak ↓ Weak Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-1134%)	-88.4% Weak ↓ Weak Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-1205%)	-45.1% Weak ↓ Weak Declining Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-664%)	3.7% Caution Caution Year-over-year change in total revenue Optimal: > 10% vs Sector: Below avg (-54%)	91.2% Excellent Excellent Year-over-year change in total revenue Optimal: > 10% vs Sector: Above avg (+1040%)	—	—
EPS Growth YoY (%)	-44.9% Weak ↓ Weak Declining Year-over-year change in earnings per share Optimal: > 10%	-10.3% Weak ↑ Weak Improving Year-over-year change in earnings per share Optimal: > 10%	-32.5% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	-16.4% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	—	—	—	—	-15.5% Weak ↓ Weak Declining Year-over-year change in earnings per share Optimal: > 10%	-34.5% Weak Weak Year-over-year change in earnings per share Optimal: > 10%	N/M	43.2% Excellent Excellent Year-over-year change in earnings per share Optimal: > 10%	N/M	—	—
Net Income Growth YoY (%)	-47.6% Weak ↓ Weak Declining Year-over-year change in net income	-28.5% Weak ↑ Weak Improving Year-over-year change in net income	-45.5% Weak ↑ Weak Improving Year-over-year change in net income	-58.9% Weak ↓ Weak Declining Year-over-year change in net income	-173.5% Weak ↓ Weak Declining Year-over-year change in net income	30.7% Excellent ↑ Excellent Improving Year-over-year change in net income	-20.6% Weak ↑ Weak Improving Year-over-year change in net income	-12.4% Weak ↑ Weak Improving Year-over-year change in net income	-33.5% Weak ↓ Weak Declining Year-over-year change in net income	-46.0% Weak Weak Year-over-year change in net income	N/M	8.2% Fair Fair Year-over-year change in net income	N/M	—	—
FCF Growth YoY (%)	-49.1% Weak ↓ Weak Declining Year-over-year change in free cash flow	-1.1% Weak ↑ Weak Improving Year-over-year change in free cash flow	-40.0% Weak Weak Year-over-year change in free cash flow	-2.0% Weak Weak Year-over-year change in free cash flow	—	—	—	—	—	—	—	—	—	—	—
Revenue CAGR 3Y (%)	-7.4% Weak Weak Compound annual revenue growth over 3 years	—	—	11.4% Good ↓ Good Declining Compound annual revenue growth over 3 years	—	369.4% Excellent ↑ Excellent Improving Compound annual revenue growth over 3 years	55.9% Excellent ↑ Excellent Improving Compound annual revenue growth over 3 years	—	-77.8% Weak ↓ Weak Declining Compound annual revenue growth over 3 years	-59.6% Weak Weak Compound annual revenue growth over 3 years	2.9% Caution Caution Compound annual revenue growth over 3 years	—	—	—	—
Revenue CAGR 5Y (%)	-25.3% Weak Weak Compound annual revenue growth over 5 years	—	—	97.9% Excellent ↑ Excellent Improving Compound annual revenue growth over 5 years	59.2% Excellent ↑ Excellent Improving Compound annual revenue growth over 5 years	15.6% Excellent ↑ Excellent Improving Compound annual revenue growth over 5 years	-24.8% Weak Weak Compound annual revenue growth over 5 years	—	-53.5% Weak Weak Compound annual revenue growth over 5 years	—	—	—	—	—	—

💰 Are margins durable? 5 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Operating Margin (%) (%)	—	—	—	—	-428.4% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-2956%)	-97.3% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-749%)	—	—	—	—	-60.1% Weak ↓ Weak Declining Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-501%)	39.1% Excellent ↑ Excellent Improving Operating income as a percentage of revenue Optimal: > 15% vs Sector: Above avg (+161%)	35.5% Excellent Excellent Operating income as a percentage of revenue Optimal: > 15% vs Sector: Above avg (+137%)	-22.0% Weak Weak Operating income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-247%)	—
Effective Tax Rate (%) (%)	-0.3% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	1.7% Excellent ↑ Excellent Improving Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.2% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	-0.1% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.0% Excellent ↓ Excellent Declining Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.9% Excellent ↑ Excellent Improving Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.1% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	0.1% Excellent Excellent Actual taxes paid relative to pre-tax income Optimal: 15-25%	—	—	—	—	—	—	—
Profit Margin (%) (%)	—	—	—	—	-427.8% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-3665%)	-89.7% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-847%)	—	—	—	—	-101.1% Weak ↓ Weak Declining Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-943%)	45.9% Excellent ↑ Excellent Improving Net income as a percentage of revenue Optimal: > 15% vs Sector: Above avg (+282%)	44.0% Excellent Excellent Net income as a percentage of revenue Optimal: > 15% vs Sector: Above avg (+267%)	-30.1% Weak Weak Net income as a percentage of revenue Optimal: > 15% vs Sector: Below avg (-351%)	—
FCF Margin (%) (%)	—	—	—	—	-388.1% Weak ↓ Weak Declining Free cash flow as a percentage of revenue Optimal: > 10%	-157.8% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	-87.2% Weak Weak Free cash flow as a percentage of revenue Optimal: > 10%	—	—	—	—	—	—	—	—
FCF / Net Income (x)	0.81x Caution → Caution Stable Free cash flow relative to reported net income Optimal: > 1x	0.79x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.86x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.81x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	0.91x Caution ↓ Caution Declining Free cash flow relative to reported net income Optimal: > 1x	1.76x Excellent ↑ Excellent Improving Free cash flow relative to reported net income Optimal: > 1x	0.14x Weak ↓ Weak Declining Free cash flow relative to reported net income Optimal: > 1x	1.02x Fair Fair Free cash flow relative to reported net income Optimal: > 1x	0.95x Caution Caution Free cash flow relative to reported net income Optimal: > 1x	—	—	—	—	—	—

🎯 Is capital allocation efficient? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Return on Invested Capital (%)	-64.3% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-36.4% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-23.0% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-17.9% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-14.4% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-18.1% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-41.6% Weak → Weak Stable Return earned on debt + equity capital invested Optimal: > 10%	-32.1% Weak ↑ Weak Improving Return earned on debt + equity capital invested Optimal: > 10%	-61.2% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-30.7% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	-12.1% Weak ↓ Weak Declining Return earned on debt + equity capital invested Optimal: > 10%	12.1% Good ↑ Good Improving Return earned on debt + equity capital invested Optimal: > 10%	-9.8% Weak Weak Return earned on debt + equity capital invested Optimal: > 10%	2.8% Weak Weak Return earned on debt + equity capital invested Optimal: > 10%	—
Return on Capital (%) (%)	-58.9% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-35.0% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-22.2% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-17.1% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-13.8% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-16.5% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-29.0% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-31.1% Weak ↑ Weak Improving Operating profit relative to total assets Optimal: > 10%	-70.6% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-36.8% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	-14.6% Weak ↓ Weak Declining Operating profit relative to total assets Optimal: > 10%	12.7% Good Good Operating profit relative to total assets Optimal: > 10%	17.8% Excellent Excellent Operating profit relative to total assets Optimal: > 10%	—	—
Return on Common Equity (%) (%)	-59.5% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-496%)	-31.0% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-307%)	-19.7% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-231%)	-17.4% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-216%)	-14.3% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-196%)	-16.8% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-212%)	-45.2% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-401%)	-33.4% Weak ↑ Weak Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-323%)	-85.4% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-670%)	-36.0% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-340%)	-25.8% Weak ↓ Weak Declining Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-272%)	17.9% Good ↑ Good Improving Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Above avg (+19%)	-15.4% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-202%)	4.8% Weak Weak Profit generated per dollar of shareholder equity Optimal: > 15% vs Sector: Below avg (-68%)	—

⚖️ Is the balance sheet risky? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Debt to Equity (x)	—	—	—	—	—	—	0.12x Excellent ↓ Excellent Declining Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-80%)	0.15x Excellent Excellent Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-76%)	0.17x Excellent Excellent Total debt relative to shareholder equity Optimal: < 0.6x vs Sector: Below avg (-72%)	—	—	—	—	—	—
Interest Coverage (x)	—	—	—	—	—	-64.67x Weak ↓ Weak Declining Operating income divided by interest expense Optimal: > 5x	-29.86x Weak Weak Operating income divided by interest expense Optimal: > 5x	-27.29x Weak Weak Operating income divided by interest expense Optimal: > 5x	—	—	—	—	151.75x Excellent Excellent Operating income divided by interest expense Optimal: > 5x	-33.90x Weak Weak Operating income divided by interest expense Optimal: > 5x	—
Net Debt (USD)	$-199.16M	$-142.71M	$-148.64M	$-57.24M	$-175.69M	$-45.01M	$-13.87M	$-52.74M	$-14.38M	$-17.09M	$-58.65M	$-72.03M	$-37.95M	$-60.16M	$-13.93M
Debt / EBITDA (x)	—	—	—	—	—	—	-0.25x Excellent ↑ Excellent Improving Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	-0.39x Excellent Excellent Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	-0.19x Excellent Excellent Debt relative to earnings before interest, taxes, depreciation Optimal: < 2x	—	—	—	—	—	—

📊 What does each share earn? 6 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Revenue per Share (USD)	$0.09	$0.00	—	$0.16	$0.42	—	—	—	$0.02	$0.12	$1.09	$8.96	$20.45	$10.78	—
Basic EPS, GAAP (USD)	$-4.36	$-3.01	$-2.73	$-2.06	$-1.77	—	—	—	$-1.71	$-1.48	$-1.10	$4.11	$2.87	$-3.24	—
Free Cash Flow per Share (USD)	$-3.53	$-2.37	$-2.34	$-1.67	$-1.64	—	—	—	$-1.61	—	—	—	—	—	—
Book Value per Share (USD)	$7.27	$9.88	$12.31	$11.53	$10.65	$4.89	$3.27	$4.01	$2.00	$3.56	$4.24	$5.13	$-58.29	$-67.70	—
Tangible Book Value per Share (USD)	$7.27	$9.88	$12.31	$11.53	$10.65	$4.89	$3.27	$4.01	$2.00	$3.56	$4.24	$5.13	$-58.29	$-67.70	—
Basic Weighted Avg Shares (shares)	79.25M	77.89M	66.89M	60.54M	43.63M	—	—	—	17.99M	15.49M	14.28M	3.17M	1.34M	1.33M	—

🏦 How resilient is the balance sheet? 3 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Working Capital (USD)	$518.86M	$599.67M	$617.69M	$577.60M	$544.70M	$167.00M	$101.49M	$117.21M	$40.74M	$62.09M	$58.08M	$70.66M	$31.67M	—	—
LT Debt (USD)	—	—	—	—	—	—	$10.89M	$15.01M	$6.10M	—	—	—	—	—	—
Total Equity (USD)	$581.76M	$754.90M	$927.92M	$721.50M	$550.03M	$171.35M	$91.98M	$103.30M	$35.93M	$63.90M	$61.03M	$72.78M	$-78.37M	$-89.86M	$-86.32M

📋 What is driving earnings? 4 metrics

Metric	FY 2025 Dec 31, 2025 10-K ↗	FY 2024 Dec 31, 2024 10-K ↗	FY 2023 Dec 31, 2023 10-K ↗	FY 2022 Dec 31, 2022 10-K ↗	FY 2021 Dec 31, 2021 10-K ↗	FY 2020 Dec 31, 2020 10-K ↗	FY 2019 Dec 31, 2019 10-K ↗	FY 2018 Dec 31, 2018 10-K ↗	FY 2017 Dec 31, 2017 10-K ↗	FY 2016 Dec 31, 2016 10-K ↗	FY 2015 Dec 31, 2015 10-K ↗	FY 2014 Dec 31, 2014 10-K ↗	FY 2013 Dec 31, 2013 10-K ↗	FY 2012 Dec 31, 2012 10-K ↗	FY 2011 Dec 31, 2011 10-K ↗
Sales/Revenue/Turnover (USD)	$7.50M	$0.00	—	$9.43M	$18.44M	$32.17M	$6.83M	—	$311.00K	$1.80M	$15.58M	$28.37M	$27.36M	$14.31M	—
Depreciation Expense (USD)	—	—	—	—	—	—	—	—	—	—	—	$738.00K	$705.00K	$786.00K	—
Net Income, GAAP (USD)	$-345.91M	$-234.33M	$-182.39M	$-125.37M	$-78.88M	$-28.84M	$-41.59M	$-34.50M	$-30.70M	$-23.00M	$-15.75M	$13.02M	$12.03M	$-4.30M	—
Operating Cash Flow (USD)	$-279.12M	$-181.39M	$-151.11M	$-98.43M	$-69.50M	$-48.12M	$-4.71M	$-34.72M	$-28.73M	—	—	—	—	—	—

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bar_chart Data from SEC EDGAR XBRL filings

Synced 1 week ago 15 years · 54 quarters

Xenon Pharmaceuticals Inc.

Analytical Summary

15-Year Financial Trajectory

Bullish Indicators

Bearish Risks

Health Breakdown

Statement lens

Benchmark Lens

Signals

Percentile Rankings

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