X4 Pharmaceuticals, Inc
XFORAnalytical Summary
X4 Pharmaceuticals, Inc faces fundamental challenges with weakness in Return on Common Equity (%). The fundamentals warrant careful consideration of downside risks.
11-Year Financial Trajectory
AnnualBullish Indicators
- No bullish signals detected.
Bearish Risks
- Operating Margin (%)Operating Margin (%) is in the bottom quartile
- Profit Margin (%)Profit Margin (%) is in the bottom quartile
- Return on Common Equity (%)Return on Common Equity (%) is in the bottom quartile
Health Breakdown
Statement lens
Choose the reporting cadence, isolate a period range, or search directly for a metric.
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ | FY 2015 Dec 31, 2015 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue Growth YoY (%) |
1273.2%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+15815%)
|
— | — | — | N/M | — | — | — | — | — | — |
| EPS Growth YoY (%) |
67.2%
Excellent
↑
Excellent
Improving
Year-over-year change in earnings per share
Optimal:
> 10%
|
66.7%
Excellent
↑
Excellent
Improving
Year-over-year change in earnings per share
Optimal:
> 10%
|
62.5%
Excellent
Excellent
Year-over-year change in earnings per share
Optimal:
> 10%
|
61.9%
Excellent
Excellent
Year-over-year change in earnings per share
Optimal:
> 10%
|
— | — | — | — | — | — | — |
| Net Income Growth YoY (%) |
-111.5%
Weak
↓
Weak
Declining
Year-over-year change in net income |
63.0%
Excellent
↑
Excellent
Improving
Year-over-year change in net income |
-7.8%
Weak
↑
Weak
Improving
Year-over-year change in net income |
-5.8%
Weak
↑
Weak
Improving
Year-over-year change in net income |
-42.8%
Weak
↓
Weak
Declining
Year-over-year change in net income |
-17.7%
Weak
↑
Weak
Improving
Year-over-year change in net income |
-58.7%
Weak
↓
Weak
Declining
Year-over-year change in net income |
1.7%
Caution
Caution
Year-over-year change in net income |
-47.5%
Weak
Weak
Year-over-year change in net income |
— | — |
| FCF Growth YoY (%) |
89.7%
Excellent
↑
Excellent
Improving
Year-over-year change in free cash flow |
-20.2%
Weak
↓
Weak
Declining
Year-over-year change in free cash flow |
55.3%
Excellent
Excellent
Year-over-year change in free cash flow |
55.9%
Excellent
Excellent
Year-over-year change in free cash flow |
— | — | — | — | — | — | — |
| Revenue CAGR 5Y (%) |
63.6%
Excellent
Excellent
Compound annual revenue growth over 5 years |
— | — | — | — | — | — | — | — | — | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ | FY 2015 Dec 31, 2015 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin (%) (%) |
-247.4%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1750%)
|
— | — | — | — | — | — | — | — | — | — |
| Effective Tax Rate (%) (%) |
-0.1%
Excellent
↑
Excellent
Improving
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-0.8%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-0.1%
Excellent
↑
Excellent
Improving
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-0.0%
Excellent
↑
Excellent
Improving
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-0.0%
Excellent
↑
Excellent
Improving
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-0.2%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
0.0%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
— | — | — | — |
| Profit Margin (%) (%) |
-225.6%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1980%)
|
— | — | — | — | — | — | — | — | — | — |
| FCF Margin (%) (%) |
-243.8%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
— | — | — | — | — | — | — | — | — | — |
| FCF / Net Income (x) |
1.08x
Fair
↓
Fair
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
3.50x
Excellent
↑
Excellent
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.95x
Caution
↑
Caution
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.82x
Caution
↓
Caution
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.80x
Caution
↓
Caution
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.95x
Caution
↑
Caution
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.91x
Caution
↑
Caution
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.76x
Caution
↓
Caution
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.82x
Caution
Caution
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.94x
Caution
Caution
Free cash flow relative to reported net income
Optimal:
> 1x
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ | FY 2015 Dec 31, 2015 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Return on Invested Capital (%) |
-33.3%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-37.8%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-101.4%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-82.2%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-87.8%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-57.0%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-34.6%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
34.3%
Excellent
↑
Excellent
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-48.6%
Weak
Weak
Return earned on debt + equity capital invested
Optimal:
> 10%
|
34.0%
Excellent
Excellent
Return earned on debt + equity capital invested
Optimal:
> 10%
|
— |
| Return on Capital (%) (%) |
-29.9%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-24.9%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-73.0%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-56.3%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-72.6%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-48.7%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-32.2%
Weak
↑
Weak
Improving
Operating profit relative to total assets
Optimal:
> 10%
|
-292.5%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
-44.5%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
— | — |
| Return on Common Equity (%) (%) |
-42.5%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-383%)
|
-169.1%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-1227%)
|
-198.0%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-1420%)
|
-126.8%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-945%)
|
-137.7%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-1018%)
|
-85.3%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-669%)
|
-40.9%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-372%)
|
43.2%
Excellent
↑
Excellent
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Above avg (+188%)
|
-57.7%
Weak
Weak
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-485%)
|
40.6%
Excellent
Excellent
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Above avg (+171%)
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ | FY 2015 Dec 31, 2015 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt to Equity (x) |
0.40x
Good
↓
Good
Declining
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-33%)
|
3.39x
Weak
↑
Weak
Improving
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Above avg (+464%)
|
1.08x
Caution
↑
Caution
Improving
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Above avg (+79%)
|
0.44x
Good
↑
Good
Improving
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-27%)
|
0.50x
Good
↑
Good
Improving
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-16%)
|
0.45x
Good
↑
Good
Improving
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-26%)
|
0.15x
Excellent
Excellent
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-74%)
|
-0.13x
Excellent
Excellent
Total debt relative to shareholder equity
Optimal:
< 0.6x
vs Sector:
Below avg (-122%)
|
— | — | — |
| Interest Coverage (x) |
-10.79x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-4.69x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-23.35x
Weak
→
Weak
Stable
Operating income divided by interest expense
Optimal:
> 5x
|
-21.93x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-23.37x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-22.27x
Weak
↑
Weak
Improving
Operating income divided by interest expense
Optimal:
> 5x
|
-24.08x
Weak
↓
Weak
Declining
Operating income divided by interest expense
Optimal:
> 5x
|
-40.40x
Weak
↓
Weak
Declining
Operating income divided by interest expense
Optimal:
> 5x
|
-17.38x
Weak
Weak
Operating income divided by interest expense
Optimal:
> 5x
|
-9.68x
Weak
Weak
Operating income divided by interest expense
Optimal:
> 5x
|
— |
| Net Debt (USD) | $-142.05M | $19.30M | $-44.22M | $-89.22M | $-49.29M | $-46.21M | $-106.18M | $1.87M | $-76.79M | — | — |
| Debt / EBITDA (x) |
-0.88x
Excellent
↑
Excellent
Improving
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-2.11x
Excellent
↓
Excellent
Declining
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-0.51x
Excellent
↓
Excellent
Declining
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-0.37x
Excellent
↑
Excellent
Improving
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-0.38x
Excellent
↑
Excellent
Improving
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-0.55x
Excellent
↓
Excellent
Declining
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-0.39x
Excellent
Excellent
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
-0.35x
Excellent
Excellent
Debt relative to earnings before interest, taxes, depreciation
Optimal:
< 2x
|
— | — | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ | FY 2015 Dec 31, 2015 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Working Capital (USD) | $235.82M | $79.30M | $99.21M | $106.35M | $73.86M | $71.36M | $119.83M | $1.43M | $68.85M | — | — |
| LT Debt (USD) | $75.00M | $75.00M | $55.00M | $32.50M | $32.50M | $32.50M | $20.00M | $10.00M | — | — | — |
| Total Equity (USD) | $186.29M | $22.15M | $51.10M | $74.05M | $64.41M | $72.80M | $129.22M | $-77.09M | $58.71M | $-56.56M | $-34.32M |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ | FY 2018 Dec 31, 2018 10-K ↗ | FY 2017 Dec 31, 2017 10-K ↗ | FY 2016 Dec 31, 2016 10-K ↗ | FY 2015 Dec 31, 2015 10-K ↗ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue/Turnover (USD) | $35.11M | $2.56M | $0.00 | $0.00 | $0.00 | $3.00M | $0.00 | — | — | — | — |
| Depreciation Expense (USD) | $1.28M | $796.00K | $419.00K | $513.00K | $499.00K | $351.00K | $103.00K | $103.00K | $195.00K | $285.00K | — |
| Net Income, GAAP (USD) | $-79.20M | $-37.45M | $-101.17M | $-93.87M | $-88.70M | $-62.13M | $-52.81M | $-33.28M | $-33.88M | $-22.98M | — |
| Operating Cash Flow (USD) | $-85.62M | $-130.90M | $-96.51M | $-77.10M | $-70.91M | $-58.82M | $-48.05M | $-25.42M | $-27.87M | $-21.64M | — |
Secondary lens
Benchmark Lens
Compare XFOR against peers after checking the statement evidence.
Open lens
Benchmark Lens
Compare XFOR against peers after checking the statement evidence.
Signals
Key bullish and bearish indicators for XFOR
No bullish signals detected
Operating Margin (%) is in the bottom quartile
Profit Margin (%) is in the bottom quartile
Return on Common Equity (%) is in the bottom quartile
Percentile Rankings
How XFOR compares to all companies
Peer Comparison
XFOR vs similar peers
Compare XFOR with peers
Stack XFOR against similar companies across every metric on this page.
north_east Open comparisonbar_chart Data from SEC EDGAR XBRL filings
Synced 1 week ago 11 years · 39 quarters