Zymeworks Inc.
ZYMEAnalytical Summary
Zymeworks Inc. faces fundamental challenges with weakness in Return on Common Equity (%) and Profit Margin (%). The fundamentals warrant careful consideration of downside risks.
7-Year Financial Trajectory
AnnualBullish Indicators
- No bullish signals detected.
Bearish Risks
- Operating Margin (%)Operating Margin (%) is in the bottom quartile
- Profit Margin (%)Profit Margin (%) is in the bottom quartile
- Return on Common Equity (%)Return on Common Equity (%) is in the bottom quartile
Health Breakdown
Statement lens
Choose the reporting cadence, isolate a period range, or search directly for a metric.
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Revenue Growth YoY (%) |
38.9%
Excellent
↓
Excellent
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+386%)
|
0.4%
Caution
↓
Caution
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Below avg (-95%)
|
-81.6%
Weak
↓
Weak
Declining
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Below avg (-1120%)
|
1446.0%
Excellent
Excellent
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Above avg (+17975%)
|
-31.5%
Weak
Weak
Year-over-year change in total revenue
Optimal:
> 10%
vs Sector:
Below avg (-494%)
|
— | — |
| EPS Growth YoY (%) |
33.3%
Excellent
Excellent
Year-over-year change in earnings per share
Optimal:
> 10%
|
5.8%
Fair
Fair
Year-over-year change in earnings per share
Optimal:
> 10%
|
N/M | N/M |
-14.8%
Weak
Weak
Year-over-year change in earnings per share
Optimal:
> 10%
|
— | — |
| Net Income Growth YoY (%) |
33.9%
Excellent
Excellent
Year-over-year change in net income |
-3.4%
Weak
Weak
Year-over-year change in net income |
N/M | N/M |
-17.3%
Weak
Weak
Year-over-year change in net income |
— | — |
| FCF Growth YoY (%) |
69.0%
Excellent
Excellent
Year-over-year change in free cash flow |
15.8%
Good
Good
Year-over-year change in free cash flow |
N/M | N/M |
-28.6%
Weak
Weak
Year-over-year change in free cash flow |
— | — |
| Revenue CAGR 3Y (%) |
-36.4%
Weak
↓
Weak
Declining
Compound annual revenue growth over 3 years |
41.9%
Excellent
Excellent
Compound annual revenue growth over 3 years |
25.0%
Excellent
Excellent
Compound annual revenue growth over 3 years |
— | — | — | — |
| Revenue CAGR 5Y (%) |
22.2%
Excellent
Excellent
Compound annual revenue growth over 5 years |
— | — | — | — | — | — |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Operating Margin (%) (%) |
-87.3%
Weak
↑
Weak
Improving
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-682%)
|
-179.7%
Weak
↓
Weak
Declining
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1298%)
|
-181.6%
Weak
↑
Weak
Improving
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1311%)
|
31.6%
Excellent
Excellent
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Above avg (+111%)
|
— |
-481.3%
Weak
Weak
Operating income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-3309%)
|
— |
| Effective Tax Rate (%) (%) |
-1.7%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-5.2%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
0.5%
Excellent
↓
Excellent
Declining
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
8.1%
Excellent
↑
Excellent
Improving
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
0.2%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
-0.2%
Excellent
Excellent
Actual taxes paid relative to pre-tax income
Optimal:
15-25%
|
— |
| Profit Margin (%) (%) |
-76.6%
Weak
↑
Weak
Improving
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-738%)
|
-160.8%
Weak
↓
Weak
Declining
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1440%)
|
-156.1%
Weak
↑
Weak
Improving
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-1401%)
|
30.1%
Excellent
Excellent
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Above avg (+151%)
|
— |
-463.5%
Weak
Weak
Net income as a percentage of revenue
Optimal:
> 15%
vs Sector:
Below avg (-3963%)
|
— |
| FCF Margin (%) (%) |
-32.6%
Weak
↑
Weak
Improving
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-146.8%
Weak
↓
Weak
Declining
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
-158.9%
Weak
↑
Weak
Improving
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
33.0%
Excellent
Excellent
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
— |
-399.8%
Weak
Weak
Free cash flow as a percentage of revenue
Optimal:
> 10%
|
— |
| FCF / Net Income (x) |
0.43x
Weak
↓
Weak
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.91x
Caution
↓
Caution
Declining
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.02x
Fair
→
Fair
Stable
Free cash flow relative to reported net income
Optimal:
> 1x
|
1.09x
Fair
↑
Fair
Improving
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.97x
Caution
Caution
Free cash flow relative to reported net income
Optimal:
> 1x
|
0.86x
Caution
Caution
Free cash flow relative to reported net income
Optimal:
> 1x
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Return on Invested Capital (%) |
-35.1%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-42.6%
Weak
↓
Weak
Declining
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-29.6%
Weak
↑
Weak
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
24.3%
Excellent
↑
Excellent
Improving
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-86.4%
Weak
Weak
Return earned on debt + equity capital invested
Optimal:
> 10%
|
-45.8%
Weak
Weak
Return earned on debt + equity capital invested
Optimal:
> 10%
|
— |
| Return on Capital (%) (%) |
-26.7%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-29.6%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
-23.8%
Weak
↓
Weak
Declining
Operating profit relative to total assets
Optimal:
> 10%
|
20.1%
Excellent
Excellent
Operating profit relative to total assets
Optimal:
> 10%
|
-55.4%
Weak
Weak
Operating profit relative to total assets
Optimal:
> 10%
|
— | — |
| Return on Common Equity (%) (%) |
-30.2%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-301%)
|
-36.2%
Weak
↓
Weak
Declining
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-341%)
|
-25.5%
Weak
↑
Weak
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-270%)
|
25.2%
Excellent
↑
Excellent
Improving
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Above avg (+68%)
|
-85.0%
Weak
Weak
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-667%)
|
-44.0%
Weak
Weak
Profit generated per dollar of shareholder equity
Optimal:
> 15%
vs Sector:
Below avg (-394%)
|
— |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Working Capital (USD) | $206.45M | $212.16M | $357.16M | $449.08M | $216.37M | — | — |
| Total Equity (USD) | $268.50M | $338.77M | $464.81M | $492.96M | $249.09M | $409.92M | $245.68M |
| Metric | FY 2025 Dec 31, 2025 10-K ↗ | FY 2024 Dec 31, 2024 10-K ↗ | FY 2023 Dec 31, 2023 10-K ↗ | FY 2022 Dec 31, 2022 10-K ↗ | FY 2021 Dec 31, 2021 10-K ↗ | FY 2020 Dec 31, 2020 10-K ↗ | FY 2019 Dec 31, 2019 10-K ↗ |
|---|---|---|---|---|---|---|---|
| Sales/Revenue/Turnover (USD) | $105.97M | $76.30M | $76.01M | $412.48M | $26.68M | $38.95M | — |
| Depreciation Expense (USD) | $3.67M | $4.19M | $7.46M | $6.22M | $3.74M | $3.35M | — |
| Net Income, GAAP (USD) | $-81.13M | $-122.69M | $-118.67M | $124.34M | $-211.84M | $-180.55M | — |
| Operating Cash Flow (USD) | $-33.01M | $-110.06M | $-118.30M | $144.11M | $-192.45M | $-151.40M | — |
Secondary lens
Benchmark Lens
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Open lens
Benchmark Lens
Compare ZYME against peers after checking the statement evidence.
Signals
Key bullish and bearish indicators for ZYME
No bullish signals detected
Operating Margin (%) is in the bottom quartile
Profit Margin (%) is in the bottom quartile
Return on Common Equity (%) is in the bottom quartile
Percentile Rankings
How ZYME compares to all companies
Peer Comparison
ZYME vs similar peers
Compare ZYME with peers
Stack ZYME against similar companies across every metric on this page.
north_east Open comparisonbar_chart Data from SEC EDGAR XBRL filings
Synced 1 week ago 7 years · 23 quarters